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Compile Data Set for Download or QSAR

Found 1 hit of ki for monomerid = 50240883   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM50240883
PNG
(CHEMBL4099357)
Show SMILES CC(C)C[C@@H]1COCc2nc(OCc3ccccn3)cc(=O)n12 |r|
Show InChI InChI=1S/C17H21N3O3/c1-12(2)7-14-10-22-11-15-19-16(8-17(21)20(14)15)23-9-13-5-3-4-6-18-13/h3-6,8,12,14H,7,9-11H2,1-2H3/t14-/m1/s1
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KEGG

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PubMed
 15n/an/an/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]MPEPy from human mGlu5 expressed in HEK293FT cell membranes after 1 hr by liquid scintillation counting

J Med Chem 60: 7764-7780 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00604
BindingDB Entry DOI: 10.7270/Q2DJ5HS8
More data for this
Ligand-Target Pair