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Compile Data Set for Download or QSAR

Found 1 hit of ki for monomerid = 50302574   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50302574
PNG
(CHEMBL576049 | N-butyl-N-ethyl-1-mesityl-3,6-dimet...)
Show SMILES CCCCN(CC)c1nc(C)nc2n(nc(C)c12)-c1c(C)cc(C)cc1C |(-8.73,6.43,;-8.72,4.89,;-7.38,4.13,;-7.38,2.59,;-6.04,1.82,;-4.71,2.59,;-4.72,4.13,;-6.04,.28,;-7.37,-.49,;-7.37,-2.03,;-8.7,-2.8,;-6.04,-2.81,;-4.7,-2.04,;-3.22,-2.51,;-2.31,-1.25,;-3.23,-0,;-2.76,1.47,;-4.7,-.48,;-2.47,-3.86,;-.93,-3.87,;-.15,-2.54,;-.18,-5.21,;-.97,-6.54,;-.22,-7.88,;-2.51,-6.51,;-3.26,-5.17,;-4.8,-5.14,)|
Show InChI InChI=1S/C22H31N5/c1-8-10-11-26(9-2)21-19-17(6)25-27(22(19)24-18(7)23-21)20-15(4)12-14(3)13-16(20)5/h12-13H,8-11H2,1-7H3
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MMDB

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Article
PubMed
 9n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP production

Bioorg Med Chem Lett 19: 6144-7 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.016
BindingDB Entry DOI: 10.7270/Q2FT8M46
More data for this
Ligand-Target Pair