BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits of ki for monomerid = 50314572   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))
BDBM50314572
PNG
((4-(3-(1,2-dimethyl-7-phenyl-1H-pyrrolo[3,2-d]pyri...)
Show SMILES Cc1cc2c(NCCCN3CCN(CC3)C(=O)c3ncccn3)nnc(-c3ccccc3)c2n1C
Show InChI InChI=1S/C26H30N8O/c1-19-18-21-23(32(19)2)22(20-8-4-3-5-9-20)30-31-24(21)27-12-7-13-33-14-16-34(17-15-33)26(35)25-28-10-6-11-29-25/h3-6,8-11,18H,7,12-17H2,1-2H3,(H,27,31)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.62E+4n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation counting


Bioorg Med Chem Lett 20: 2163-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.044
BindingDB Entry DOI: 10.7270/Q2NK3F54
More data for this
Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D


(Homo sapiens (Human))
BDBM50314572
PNG
((4-(3-(1,2-dimethyl-7-phenyl-1H-pyrrolo[3,2-d]pyri...)
Show SMILES Cc1cc2c(NCCCN3CCN(CC3)C(=O)c3ncccn3)nnc(-c3ccccc3)c2n1C
Show InChI InChI=1S/C26H30N8O/c1-19-18-21-23(32(19)2)22(20-8-4-3-5-9-20)30-31-24(21)27-12-7-13-33-14-16-34(17-15-33)26(35)25-28-10-6-11-29-25/h3-6,8-11,18H,7,12-17H2,1-2H3,(H,27,31)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+5n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Displacement of [methyl-3H]rolipram from PDE4D4 expressed in CHO cells after 1 hr by scintillation counting


Bioorg Med Chem Lett 20: 2163-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.044
BindingDB Entry DOI: 10.7270/Q2NK3F54
More data for this
Ligand-Target Pair