Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytosol aminopeptidase [33-68,L62W] (Sus scrofa (Pig)) | BDBM50337147 ((RS)-1-amino-3-cyclohexylpropylphosphonic acid | C...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Inhibition of porcine kidney leucine aminopeptidase M17 using Leu-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition meas... | Eur J Med Chem 117: 187-96 (2016) Article DOI: 10.1016/j.ejmech.2016.04.018 BindingDB Entry DOI: 10.7270/Q2BC41F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methionine aminopeptidase 1 (Homo sapiens (Human)) | BDBM50337147 ((RS)-1-amino-3-cyclohexylpropylphosphonic acid | C...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of Human MetAP1b using Met-pNA as substrate | J Med Chem 58: 2350-7 (2015) Article DOI: 10.1021/jm501790e BindingDB Entry DOI: 10.7270/Q2C53NJX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aminopeptidase N (Sus scrofa (Pig)) | BDBM50337147 ((RS)-1-amino-3-cyclohexylpropylphosphonic acid | C...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.71E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wroclaw University of Technology Curated by ChEMBL | Assay Description Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f... | Eur J Med Chem 117: 187-96 (2016) Article DOI: 10.1016/j.ejmech.2016.04.018 BindingDB Entry DOI: 10.7270/Q2BC41F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aminopeptidase N (Sus scrofa (Pig)) | BDBM50337147 ((RS)-1-amino-3-cyclohexylpropylphosphonic acid | C...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.71E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trinity College Curated by ChEMBL | Assay Description Inhibition of pig kidney microsomal aminopeptidase N | Antimicrob Agents Chemother 52: 3221-8 (2008) Article DOI: 10.1128/AAC.01327-07 BindingDB Entry DOI: 10.7270/Q2S75GMX | |||||||||||
More data for this Ligand-Target Pair |