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Compile Data Set for Download or QSAR

Found 1 hit of ki for monomerid = 50343238   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform


(Homo sapiens (Human))		BDBM50343238
PNG
(CHEMBL1773564 | N-(6-(2-(4-Methoxybenzyloxy)pyrimi...)
Show SMILES COc1ccc(COc2nccc(n2)-c2ccc3nc(NC(C)=O)sc3c2)cc1
Show InChI InChI=1S/C21H18N4O3S/c1-13(26)23-21-25-18-8-5-15(11-19(18)29-21)17-9-10-22-20(24-17)28-12-14-3-6-16(27-2)7-4-14/h3-11H,12H2,1-2H3,(H,23,25,26)
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Article
PubMed
 58n/an/an/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of human PI3Kalpha expressed in Sf9 cells

J Med Chem 54: 1789-811 (2011)


Article DOI: 10.1021/jm1014605
BindingDB Entry DOI: 10.7270/Q2TH8N1K
More data for this
Ligand-Target Pair