Found 4 hits of ki for monomerid = 50349333 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Prothrombin
(Homo sapiens (Human)) | BDBM50349333
(CHEMBL1809238)Show SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](CCC(=O)N2CCN(CC2)c2ncccn2)NS(=O)(=O)Cc2ccccc2)cc1 |r| Show InChI InChI=1S/C33H41N9O5S/c34-30(35)26-11-9-24(10-12-26)22-38-31(44)28-8-4-17-42(28)32(45)27(39-48(46,47)23-25-6-2-1-3-7-25)13-14-29(43)40-18-20-41(21-19-40)33-36-15-5-16-37-33/h1-3,5-7,9-12,15-16,27-28,39H,4,8,13-14,17-23H2,(H3,34,35)(H,38,44)/t27-,28+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg
Curated by ChEMBL
| Assay Description
Inhibition of thrombin |
Bioorg Med Chem Lett 21: 4860-4 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.033
BindingDB Entry DOI: 10.7270/Q2ST7Q5M |
More data for this
Ligand-Target Pair | |
Transmembrane protease serine 11D
(Homo sapiens (Human)) | BDBM50349333
(CHEMBL1809238)Show SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](CCC(=O)N2CCN(CC2)c2ncccn2)NS(=O)(=O)Cc2ccccc2)cc1 |r| Show InChI InChI=1S/C33H41N9O5S/c34-30(35)26-11-9-24(10-12-26)22-38-31(44)28-8-4-17-42(28)32(45)27(39-48(46,47)23-25-6-2-1-3-7-25)13-14-29(43)40-18-20-41(21-19-40)33-36-15-5-16-37-33/h1-3,5-7,9-12,15-16,27-28,39H,4,8,13-14,17-23H2,(H3,34,35)(H,38,44)/t27-,28+/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant airway trypsin-like protease HAT using D-cyclohexylalanine-Pro-Arg-AMC as substrate by fluorescence plate reader anal... |
Bioorg Med Chem Lett 21: 4860-4 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.033
BindingDB Entry DOI: 10.7270/Q2ST7Q5M |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50349333
(CHEMBL1809238)Show SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](CCC(=O)N2CCN(CC2)c2ncccn2)NS(=O)(=O)Cc2ccccc2)cc1 |r| Show InChI InChI=1S/C33H41N9O5S/c34-30(35)26-11-9-24(10-12-26)22-38-31(44)28-8-4-17-42(28)32(45)27(39-48(46,47)23-25-6-2-1-3-7-25)13-14-29(43)40-18-20-41(21-19-40)33-36-15-5-16-37-33/h1-3,5-7,9-12,15-16,27-28,39H,4,8,13-14,17-23H2,(H3,34,35)(H,38,44)/t27-,28+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 129 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg
Curated by ChEMBL
| Assay Description
Inhibition of factor 10a |
Bioorg Med Chem Lett 21: 4860-4 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.033
BindingDB Entry DOI: 10.7270/Q2ST7Q5M |
More data for this
Ligand-Target Pair | |
Plasminogen
(Homo sapiens (Human)) | BDBM50349333
(CHEMBL1809238)Show SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](CCC(=O)N2CCN(CC2)c2ncccn2)NS(=O)(=O)Cc2ccccc2)cc1 |r| Show InChI InChI=1S/C33H41N9O5S/c34-30(35)26-11-9-24(10-12-26)22-38-31(44)28-8-4-17-42(28)32(45)27(39-48(46,47)23-25-6-2-1-3-7-25)13-14-29(43)40-18-20-41(21-19-40)33-36-15-5-16-37-33/h1-3,5-7,9-12,15-16,27-28,39H,4,8,13-14,17-23H2,(H3,34,35)(H,38,44)/t27-,28+/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg
Curated by ChEMBL
| Assay Description
Inhibition of plasmin |
Bioorg Med Chem Lett 21: 4860-4 (2011)
Article DOI: 10.1016/j.bmcl.2011.06.033
BindingDB Entry DOI: 10.7270/Q2ST7Q5M |
More data for this
Ligand-Target Pair | |
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