BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit of ki for monomerid = 50352513   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Trypanothione reductase


(Trypanosoma cruzi)		BDBM50352513
PNG
(CHEMBL1824853)
Show SMILES COCCn1c(SCC(=O)CNc2ccc(cc2)S(=O)(=O)N2CCCCC2)ncc1-c1ccccc1
Show InChI InChI=1S/C26H32N4O4S2/c1-34-17-16-30-25(21-8-4-2-5-9-21)19-28-26(30)35-20-23(31)18-27-22-10-12-24(13-11-22)36(32,33)29-14-6-3-7-15-29/h2,4-5,8-13,19,27H,3,6-7,14-18,20H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
 1.11E+4n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi TryR using trypanothione as substrate preincubated for 10 mins

Bioorg Med Chem Lett 21: 5255-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.07.036
BindingDB Entry DOI: 10.7270/Q2ZP46HX
More data for this
Ligand-Target Pair