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Compile Data Set for Download or QSAR

Found 1 hit of ki for monomerid = 50355473   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50355473
PNG
(CHEMBL1835662)
Show SMILES COc1ccc(Nc2nc(N)n(n2)-c2ccc(cc2)C#N)cc1OC
Show InChI InChI=1S/C17H16N6O2/c1-24-14-8-5-12(9-15(14)25-2)20-17-21-16(19)23(22-17)13-6-3-11(10-18)4-7-13/h3-9H,1-2H3,(H3,19,20,21,22)
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Similars

Article
PubMed
22n/an/an/an/an/an/an/an/a



Vertex Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Displacement of [33P]ATP from human recombinant FLT3 domain after 20 mins by scintillation counting


J Med Chem 54: 7184-92 (2011)


Article DOI: 10.1021/jm200712h
BindingDB Entry DOI: 10.7270/Q2DZ08QQ
More data for this
Ligand-Target Pair