Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
S-adenosylmethionine decarboxylase proenzyme (Rattus norvegicus) | BDBM50366942 (CHEMBL540135) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory activity against S-adenosyl-L-methionine decarboxylase using liver from rat in presence of 1 mM putrescine | J Med Chem 25: 550-6 (1982) BindingDB Entry DOI: 10.7270/Q2VX0H37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
S-adenosylmethionine decarboxylase proenzyme (Rattus norvegicus) | BDBM50366942 (CHEMBL540135) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory activity against S-adenosyl-L-methionine decarboxylase using liver from rat in presence of 1 mM putrescine | J Med Chem 25: 550-6 (1982) BindingDB Entry DOI: 10.7270/Q2VX0H37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty acid synthase (Homo sapiens (Human)) | BDBM50366942 (CHEMBL540135) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Pierre et Marie Curie Curated by ChEMBL | Assay Description Inhibition constant against Escherichia coli cyclopropane fatty acid synthase | Bioorg Med Chem Lett 14: 1661-4 (2004) Article DOI: 10.1016/j.bmcl.2004.01.051 BindingDB Entry DOI: 10.7270/Q26H4HZX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Catechol O-methyltransferase (Homo sapiens (Human)) | BDBM50366942 (CHEMBL540135) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 6.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was tested for inhibition of Catechol O-methyltransferase using radiochemical assay | J Med Chem 24: 1271-7 (1982) BindingDB Entry DOI: 10.7270/Q26D5TJM | |||||||||||
More data for this Ligand-Target Pair |