BindingDB PrimarySearch

Found 7 hits of ki for monomerid = 50370987
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carbonic anhydrase (Candida glabrata)	BDBM50370987 (TAVABOROLE) Show SMILES OB1OCc2cc(F)ccc12 Show InChI	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem	Article PubMed	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Montpellier Curated by ChEMBL					Assay Description The compound was tested for inhibition of rat plasma renin at pH of 6.0.				ACS Med Chem Lett 8: 1194-1198 (2017) Article DOI: 10.1021/acsmedchemlett.7b00369 BindingDB Entry DOI: 10.7270/Q2SN0CHK
University of Montpellier Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase (Cryptococcus neoformans var. grubii (Filobasidiell...)	BDBM50370987 (TAVABOROLE) Show SMILES OB1OCc2cc(F)ccc12 Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem	Article PubMed	89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Montpellier Curated by ChEMBL					Assay Description Inhibition of Cryptococcus neoformans Can2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assay				ACS Med Chem Lett 8: 1194-1198 (2017) Article DOI: 10.1021/acsmedchemlett.7b00369 BindingDB Entry DOI: 10.7270/Q2SN0CHK
University of Montpellier Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50370987 (TAVABOROLE) Show SMILES OB1OCc2cc(F)ccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem	Article PubMed	462	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Montpellier Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase-2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assay				ACS Med Chem Lett 8: 1194-1198 (2017) Article DOI: 10.1021/acsmedchemlett.7b00369 BindingDB Entry DOI: 10.7270/Q2SN0CHK
University of Montpellier Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50370987 (TAVABOROLE) Show SMILES OB1OCc2cc(F)ccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem	Article PubMed	462	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human carbonic anhydrase 2 incubated for 30 mins prior to testing measured for 10 to 100 secs by phenol red-based stopped-flow CO2 hydr...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00403 BindingDB Entry DOI: 10.7270/Q24171SK
TBA					More data for this Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic (Saccharomyces cerevisiae S288c)	BDBM50370987 (TAVABOROLE) Show SMILES OB1OCc2cc(F)ccc12 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem	Article PubMed	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Anacor Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Saccharomyces cerevisiae cytoplasmic leucyl-tRNA synthetase after 20 mins				Science 316: 1759-1761 (2007) Article DOI: 10.1126/science.1142189 BindingDB Entry DOI: 10.7270/Q2P84CQ2
Anacor Pharmaceuticals, Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50370987 (TAVABOROLE) Show SMILES OB1OCc2cc(F)ccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem	Article PubMed	2.02E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Montpellier Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase-1 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assay				ACS Med Chem Lett 8: 1194-1198 (2017) Article DOI: 10.1021/acsmedchemlett.7b00369 BindingDB Entry DOI: 10.7270/Q2SN0CHK
University of Montpellier Curated by ChEMBL					More data for this Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic (Saccharomyces cerevisiae S288c)	BDBM50370987 (TAVABOROLE) Show SMILES OB1OCc2cc(F)ccc12 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem	Article PubMed	3.14E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Anacor Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Saccharomyces cerevisiae cytoplasmic leucyl-tRNA synthetase after 2 mins				Science 316: 1759-1761 (2007) Article DOI: 10.1126/science.1142189 BindingDB Entry DOI: 10.7270/Q2P84CQ2
Anacor Pharmaceuticals, Inc Curated by ChEMBL					More data for this Ligand-Target Pair