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Compile Data Set for Download or QSAR

Found 2 hits of ki for monomerid = 50382582   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein KIF11


(Homo sapiens (Human))
BDBM50382582
PNG
(CHEMBL2022999)
Show SMILES Cc1ccc(cc1)C(CCC(N)C(O)=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C24H25NO2/c1-18-12-14-21(15-13-18)24(17-16-22(25)23(26)27,19-8-4-2-5-9-19)20-10-6-3-7-11-20/h2-15,22H,16-17,25H2,1H3,(H,26,27)
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
7.5n/an/an/an/an/an/an/an/a



The Beatson Institute for Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...


J Med Chem 55: 1511-25 (2012)


Article DOI: 10.1021/jm201195m
BindingDB Entry DOI: 10.7270/Q2CZ386T
More data for this
Ligand-Target Pair
Kinesin-like protein KIF11


(Homo sapiens (Human))
BDBM50382582
PNG
(CHEMBL2022999)
Show SMILES Cc1ccc(cc1)C(CCC(N)C(O)=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C24H25NO2/c1-18-12-14-21(15-13-18)24(17-16-22(25)23(26)27,19-8-4-2-5-9-19)20-10-6-3-7-11-20/h2-15,22H,16-17,25H2,1H3,(H,26,27)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
9.80n/an/an/an/an/an/an/an/a



The Beatson Institute for Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...


J Med Chem 55: 1511-25 (2012)


Article DOI: 10.1021/jm201195m
BindingDB Entry DOI: 10.7270/Q2CZ386T
More data for this
Ligand-Target Pair