Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50382706 (Benzyldithiocarbamate sodium salt (I) | CHEMBL2023...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human CA2 pre-incubated for 15 mins by stopped-flow CO2 hydration method | J Med Chem 55: 1721-30 (2012) Article DOI: 10.1021/jm300031j BindingDB Entry DOI: 10.7270/Q2GQ6ZSC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase (Drosophila melanogaster) | BDBM50382706 (Benzyldithiocarbamate sodium salt (I) | CHEMBL2023...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tampere and Tampere University Hospital Curated by ChEMBL | Assay Description Inhibition of Drosophila melanogaster recombinant carbonic anhydrase-1 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins by CO2 hydra... | Bioorg Med Chem 21: 1516-21 (2013) Article DOI: 10.1016/j.bmc.2012.08.046 BindingDB Entry DOI: 10.7270/Q2HT2QNH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50382706 (Benzyldithiocarbamate sodium salt (I) | CHEMBL2023...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human CA1 pre-incubated for 15 mins by stopped-flow CO2 hydration method | J Med Chem 55: 1721-30 (2012) Article DOI: 10.1021/jm300031j BindingDB Entry DOI: 10.7270/Q2GQ6ZSC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 12 (Homo sapiens (Human)) | BDBM50382706 (Benzyldithiocarbamate sodium salt (I) | CHEMBL2023...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human CA12 pre-incubated for 15 mins by stopped-flow CO2 hydration method | J Med Chem 55: 1721-30 (2012) Article DOI: 10.1021/jm300031j BindingDB Entry DOI: 10.7270/Q2GQ6ZSC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 9 (Homo sapiens (Human)) | BDBM50382706 (Benzyldithiocarbamate sodium salt (I) | CHEMBL2023...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of human CA9 pre-incubated for 15 mins by stopped-flow CO2 hydration method | J Med Chem 55: 1721-30 (2012) Article DOI: 10.1021/jm300031j BindingDB Entry DOI: 10.7270/Q2GQ6ZSC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
LD26647p (Drosophila melanogaster) | BDBM50382706 (Benzyldithiocarbamate sodium salt (I) | CHEMBL2023...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 213 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tampere and Tampere University Hospital Curated by ChEMBL | Assay Description Inhibition of Drosophila melanogaster recombinant carbonic anhydrase-2 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins by CO2 hydra... | Bioorg Med Chem 21: 1516-21 (2013) Article DOI: 10.1016/j.bmc.2012.08.046 BindingDB Entry DOI: 10.7270/Q2HT2QNH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyphenol oxidase 1 (Agaricus bisporus (White button mushroom)) | BDBM50382706 (Benzyldithiocarbamate sodium salt (I) | CHEMBL2023...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.70E+3 | -31.1 | n/a | n/a | n/a | n/a | n/a | 6.8 | 37 |
University of Tehran | Assay Description The assay was performed as previously described with slight modifications [Chen et al., J. Agric. Food Chem., 50:4108-12]. The reaction medium was 1 ... | J Enzyme Inhib Med Chem 25: 272-81 (2010) Article DOI: 10.1080/14756360903179351 BindingDB Entry DOI: 10.7270/Q2000101 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyphenol oxidase 1 (Agaricus bisporus (White button mushroom)) | BDBM50382706 (Benzyldithiocarbamate sodium salt (I) | CHEMBL2023...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.90E+3 | -31.0 | n/a | n/a | n/a | n/a | n/a | 6.8 | 37 |
University of Tehran | Assay Description The assay was performed as previously described with slight modifications [Chen et al., J. Agric. Food Chem., 50:4108-12]. The reaction medium was 1 ... | J Enzyme Inhib Med Chem 25: 272-81 (2010) Article DOI: 10.1080/14756360903179351 BindingDB Entry DOI: 10.7270/Q2000101 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyphenol oxidase 1 (Agaricus bisporus (White button mushroom)) | BDBM50382706 (Benzyldithiocarbamate sodium salt (I) | CHEMBL2023...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9.40E+3 | -28.9 | n/a | n/a | n/a | n/a | n/a | 6.8 | 27 |
University of Tehran | Assay Description The assay was performed as previously described with slight modifications [Chen et al., J. Agric. Food Chem., 50:4108-12]. The reaction medium was 1 ... | J Enzyme Inhib Med Chem 25: 272-81 (2010) Article DOI: 10.1080/14756360903179351 BindingDB Entry DOI: 10.7270/Q2000101 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Polyphenol oxidase 1 (Agaricus bisporus (White button mushroom)) | BDBM50382706 (Benzyldithiocarbamate sodium salt (I) | CHEMBL2023...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.41E+4 | -27.9 | n/a | n/a | n/a | n/a | n/a | 6.8 | 27 |
University of Tehran | Assay Description The assay was performed as previously described with slight modifications [Chen et al., J. Agric. Food Chem., 50:4108-12]. The reaction medium was 1 ... | J Enzyme Inhib Med Chem 25: 272-81 (2010) Article DOI: 10.1080/14756360903179351 BindingDB Entry DOI: 10.7270/Q2000101 | |||||||||||
More data for this Ligand-Target Pair |