Found 8 hits of ki for monomerid = 50387143 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50387143
(CHEMBL2047823)Show SMILES NS(=O)(=O)Oc1ccc(NC(=O)Nc2cccc(Oc3ccccc3)c2)cc1 Show InChI InChI=1S/C19H17N3O5S/c20-28(24,25)27-17-11-9-14(10-12-17)21-19(23)22-15-5-4-8-18(13-15)26-16-6-2-1-3-7-16/h1-13H,(H2,20,24,25)(H2,21,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 78 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ecole Nationale Sup£rieure de Chimie de Montpellier
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase 12 preincubated for 15 mins measured for 10 to 100 sec using phenol red indicator-based stopped flow assay |
Bioorg Med Chem Lett 22: 4681-5 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.083
BindingDB Entry DOI: 10.7270/Q20866C2 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50387143
(CHEMBL2047823)Show SMILES NS(=O)(=O)Oc1ccc(NC(=O)Nc2cccc(Oc3ccccc3)c2)cc1 Show InChI InChI=1S/C19H17N3O5S/c20-28(24,25)27-17-11-9-14(10-12-17)21-19(23)22-15-5-4-8-18(13-15)26-16-6-2-1-3-7-16/h1-13H,(H2,20,24,25)(H2,21,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 86 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Romanian Academy
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase-12 |
Bioorg Med Chem 21: 1404-9 (2013)
Article DOI: 10.1016/j.bmc.2012.11.004
BindingDB Entry DOI: 10.7270/Q2XW4M4Q |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50387143
(CHEMBL2047823)Show SMILES NS(=O)(=O)Oc1ccc(NC(=O)Nc2cccc(Oc3ccccc3)c2)cc1 Show InChI InChI=1S/C19H17N3O5S/c20-28(24,25)27-17-11-9-14(10-12-17)21-19(23)22-15-5-4-8-18(13-15)26-16-6-2-1-3-7-16/h1-13H,(H2,20,24,25)(H2,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 108 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Romanian Academy
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase-9 |
Bioorg Med Chem 21: 1404-9 (2013)
Article DOI: 10.1016/j.bmc.2012.11.004
BindingDB Entry DOI: 10.7270/Q2XW4M4Q |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50387143
(CHEMBL2047823)Show SMILES NS(=O)(=O)Oc1ccc(NC(=O)Nc2cccc(Oc3ccccc3)c2)cc1 Show InChI InChI=1S/C19H17N3O5S/c20-28(24,25)27-17-11-9-14(10-12-17)21-19(23)22-15-5-4-8-18(13-15)26-16-6-2-1-3-7-16/h1-13H,(H2,20,24,25)(H2,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 115 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ecole Nationale Sup£rieure de Chimie de Montpellier
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase 9 preincubated for 15 mins measured for 10 to 100 sec using phenol red indicator-based stopped flow assay |
Bioorg Med Chem Lett 22: 4681-5 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.083
BindingDB Entry DOI: 10.7270/Q20866C2 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50387143
(CHEMBL2047823)Show SMILES NS(=O)(=O)Oc1ccc(NC(=O)Nc2cccc(Oc3ccccc3)c2)cc1 Show InChI InChI=1S/C19H17N3O5S/c20-28(24,25)27-17-11-9-14(10-12-17)21-19(23)22-15-5-4-8-18(13-15)26-16-6-2-1-3-7-16/h1-13H,(H2,20,24,25)(H2,21,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 858 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Romanian Academy
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase-2 |
Bioorg Med Chem 21: 1404-9 (2013)
Article DOI: 10.1016/j.bmc.2012.11.004
BindingDB Entry DOI: 10.7270/Q2XW4M4Q |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50387143
(CHEMBL2047823)Show SMILES NS(=O)(=O)Oc1ccc(NC(=O)Nc2cccc(Oc3ccccc3)c2)cc1 Show InChI InChI=1S/C19H17N3O5S/c20-28(24,25)27-17-11-9-14(10-12-17)21-19(23)22-15-5-4-8-18(13-15)26-16-6-2-1-3-7-16/h1-13H,(H2,20,24,25)(H2,21,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 902 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ecole Nationale Sup£rieure de Chimie de Montpellier
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec using phenol red indicator-based stopped flow assay |
Bioorg Med Chem Lett 22: 4681-5 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.083
BindingDB Entry DOI: 10.7270/Q20866C2 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50387143
(CHEMBL2047823)Show SMILES NS(=O)(=O)Oc1ccc(NC(=O)Nc2cccc(Oc3ccccc3)c2)cc1 Show InChI InChI=1S/C19H17N3O5S/c20-28(24,25)27-17-11-9-14(10-12-17)21-19(23)22-15-5-4-8-18(13-15)26-16-6-2-1-3-7-16/h1-13H,(H2,20,24,25)(H2,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Romanian Academy
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase-1 |
Bioorg Med Chem 21: 1404-9 (2013)
Article DOI: 10.1016/j.bmc.2012.11.004
BindingDB Entry DOI: 10.7270/Q2XW4M4Q |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50387143
(CHEMBL2047823)Show SMILES NS(=O)(=O)Oc1ccc(NC(=O)Nc2cccc(Oc3ccccc3)c2)cc1 Show InChI InChI=1S/C19H17N3O5S/c20-28(24,25)27-17-11-9-14(10-12-17)21-19(23)22-15-5-4-8-18(13-15)26-16-6-2-1-3-7-16/h1-13H,(H2,20,24,25)(H2,21,22,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ecole Nationale Sup£rieure de Chimie de Montpellier
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase 1 preincubated for 15 mins measured for 10 to 100 sec using phenol red indicator-based stopped flow assay |
Bioorg Med Chem Lett 22: 4681-5 (2012)
Article DOI: 10.1016/j.bmcl.2012.05.083
BindingDB Entry DOI: 10.7270/Q20866C2 |
More data for this
Ligand-Target Pair | |
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