Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50401947 (CHEMBL2207638) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich Alexander University Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from human dopamine D2short receptor expressed in CHO cells after 60 mins by scintillation counting analysis | Bioorg Med Chem Lett 22: 7151-4 (2012) Article DOI: 10.1016/j.bmcl.2012.09.064 BindingDB Entry DOI: 10.7270/Q2Q52QSM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50401947 (CHEMBL2207638) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich Alexander University Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from human dopamine D2long receptor expressed in CHO cells after 60 mins by scintillation counting analysis | Bioorg Med Chem Lett 22: 7151-4 (2012) Article DOI: 10.1016/j.bmcl.2012.09.064 BindingDB Entry DOI: 10.7270/Q2Q52QSM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50401947 (CHEMBL2207638) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich Alexander University Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells after 60 mins by scintillation counting analysis | Bioorg Med Chem Lett 22: 7151-4 (2012) Article DOI: 10.1016/j.bmcl.2012.09.064 BindingDB Entry DOI: 10.7270/Q2Q52QSM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (PIG) | BDBM50401947 (CHEMBL2207638) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich Alexander University Curated by ChEMBL | Assay Description Displacement of [3H]ketanserin from 5-HT2 receptor in porcine cerebral cortex homogenate after 60 mins by scintillation counting analysis | Bioorg Med Chem Lett 22: 7151-4 (2012) Article DOI: 10.1016/j.bmcl.2012.09.064 BindingDB Entry DOI: 10.7270/Q2Q52QSM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Sus scrofa) | BDBM50401947 (CHEMBL2207638) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich Alexander University Curated by ChEMBL | Assay Description Displacement of [3H]SCH23390 from dopamine D1 receptor in porcine striatal membranes after 60 mins by scintillation counting analysis | Bioorg Med Chem Lett 22: 7151-4 (2012) Article DOI: 10.1016/j.bmcl.2012.09.064 BindingDB Entry DOI: 10.7270/Q2Q52QSM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H2 receptor (Homo sapiens (Human)) | BDBM50401947 (CHEMBL2207638) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich Alexander University Curated by ChEMBL | Assay Description Displacement of [3H]URDE257 from human histamine H2 receptor expressed in insect Sf9 cell membrane preparation after 60 mins by scintillation countin... | Bioorg Med Chem Lett 22: 7151-4 (2012) Article DOI: 10.1016/j.bmcl.2012.09.064 BindingDB Entry DOI: 10.7270/Q2Q52QSM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H1 receptor (Homo sapiens (Human)) | BDBM50401947 (CHEMBL2207638) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich Alexander University Curated by ChEMBL | Assay Description Displacement of [3H]mepyramine from human histamine H1 receptor expressed in insect Sf9 cell membrane preparation after 60 mins by scintillation coun... | Bioorg Med Chem Lett 22: 7151-4 (2012) Article DOI: 10.1016/j.bmcl.2012.09.064 BindingDB Entry DOI: 10.7270/Q2Q52QSM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50401947 (CHEMBL2207638) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich Alexander University Curated by ChEMBL | Assay Description Displacement of [3H]Nalpha-methylhistamine from human histamine H3 receptor expressed in insect Sf9 cell membrane preparation after 60 mins by scinti... | Bioorg Med Chem Lett 22: 7151-4 (2012) Article DOI: 10.1016/j.bmcl.2012.09.064 BindingDB Entry DOI: 10.7270/Q2Q52QSM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H4 receptor (Homo sapiens (Human)) | BDBM50401947 (CHEMBL2207638) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich Alexander University Curated by ChEMBL | Assay Description Displacement of [3H]UR-PI294 from human histamine H4 receptor expressed in insect Sf9 cell membrane preparation after 60 mins by scintillation counti... | Bioorg Med Chem Lett 22: 7151-4 (2012) Article DOI: 10.1016/j.bmcl.2012.09.064 BindingDB Entry DOI: 10.7270/Q2Q52QSM | |||||||||||
More data for this Ligand-Target Pair |