BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits of ki for monomerid = 50402820   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50402820
PNG
(CHEMBL2208430)
Show SMILES O[C@H](CNC(=O)c1c[nH]c2ccccc12)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 |r|
Show InChI InChI=1S/C23H25Cl2N3O3/c24-20-6-5-17(11-21(20)25)31-16-7-9-28(10-8-16)14-15(29)12-27-23(30)19-13-26-22-4-2-1-3-18(19)22/h1-6,11,13,15-16,26,29H,7-10,12,14H2,(H,27,30)/t15-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2.51n/an/an/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Displacement of [3H]-4-(2,4-dichloro-3-methylphenoxy)-l'-[4- (methylsulfonyl)benzoyl]-l,4'-bipiperidine from human recombinant CCR3 expressed in CHOK...


Bioorg Med Chem Lett 22: 7702-6 (2012)


Article DOI: 10.1016/j.bmcl.2012.09.113
BindingDB Entry DOI: 10.7270/Q2CJ8FNG
More data for this
Ligand-Target Pair
Histamine H1 receptor


(Homo sapiens (Human))
BDBM50402820
PNG
(CHEMBL2208430)
Show SMILES O[C@H](CNC(=O)c1c[nH]c2ccccc12)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1 |r|
Show InChI InChI=1S/C23H25Cl2N3O3/c24-20-6-5-17(11-21(20)25)31-16-7-9-28(10-8-16)14-15(29)12-27-23(30)19-13-26-22-4-2-1-3-18(19)22/h1-6,11,13,15-16,26,29H,7-10,12,14H2,(H,27,30)/t15-/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
31.6n/an/an/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Displacement of [3H]-pyrilamine from human histamine H1 receptor expressed in recombinant CHOK1 cells after 1 hr


Bioorg Med Chem Lett 22: 7702-6 (2012)


Article DOI: 10.1016/j.bmcl.2012.09.113
BindingDB Entry DOI: 10.7270/Q2CJ8FNG
More data for this
Ligand-Target Pair