Compile Data Set for Download or QSAR

Found 4 hits of ki for monomerid = 50434274   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Isocitrate dehydrogenase [NADP] cytoplasmic (Homo sapiens (Human))	BDBM50434274 (CHEMBL2386129) Show SMILES CC(C)c1cc(Cc2ccccc2)n(O)c(=O)c1 Show InChI InChI=1S/C15H17NO2/c1-11(2)13-9-14(16(18)15(17)10-13)8-12-6-4-3-5-7-12/h3-7,9-11,18H,8H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of human IDH1 R132C mutant expressed in Escherichia coli BL21-CodonPlus assessed as reduction in NADPH consumption				J Med Chem 57: 8307-18 (2014) Article DOI: 10.1021/jm500660f BindingDB Entry DOI: 10.7270/Q23J3FJR
					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic (Homo sapiens (Human))	BDBM50434274 (CHEMBL2386129) Show SMILES CC(C)c1cc(Cc2ccccc2)n(O)c(=O)c1 Show InChI InChI=1S/C15H17NO2/c1-11(2)13-9-14(16(18)15(17)10-13)8-12-6-4-3-5-7-12/h3-7,9-11,18H,8H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of human IDH1 R132H mutant expressed in Escherichia coli BL21-CodonPlus assessed as reduction in NADPH consumption				J Med Chem 57: 8307-18 (2014) Article DOI: 10.1021/jm500660f BindingDB Entry DOI: 10.7270/Q23J3FJR
					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic (Homo sapiens (Human))	BDBM50434274 (CHEMBL2386129) Show SMILES CC(C)c1cc(Cc2ccccc2)n(O)c(=O)c1 Show InChI InChI=1S/C15H17NO2/c1-11(2)13-9-14(16(18)15(17)10-13)8-12-6-4-3-5-7-12/h3-7,9-11,18H,8H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of wild type IDH1 (unknown origin) expressed in Escherichia coli BL21 using alpha-ketoglutarate as substrate incubated for 5 mins prior to...				ACS Med Chem Lett 4: 542-546 (2013) Article DOI: 10.1021/ml400036z BindingDB Entry DOI: 10.7270/Q2T72JS5
					More data for this Ligand-Target Pair
Isocitrate dehydrogenase [NADP] cytoplasmic (Homo sapiens (Human))	BDBM50434274 (CHEMBL2386129) Show SMILES CC(C)c1cc(Cc2ccccc2)n(O)c(=O)c1 Show InChI InChI=1S/C15H17NO2/c1-11(2)13-9-14(16(18)15(17)10-13)8-12-6-4-3-5-7-12/h3-7,9-11,18H,8H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of wild type human IDH1 expressed in Escherichia coli BL21-CodonPlus assessed as reduction in NADPH consumption				J Med Chem 57: 8307-18 (2014) Article DOI: 10.1021/jm500660f BindingDB Entry DOI: 10.7270/Q23J3FJR
					More data for this Ligand-Target Pair