Found 216 hits of ki for monomerid = 55121 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| DrugBank PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich-Alexander University
Curated by ChEMBL
| Assay Description Binding Affinity was tested on the high affinity site of Dopamine receptor D4.4 |
J Med Chem 43: 756-62 (2000)
BindingDB Entry DOI: 10.7270/Q27W6CXP |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(BOVINE) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
UniProtKB/SwissProt
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| PubMed
| 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich-Alexander University
Curated by ChEMBL
| Assay Description Binding Affinity on high Affinity Site of Bovine dopamine receptor D2. Tested for ability to displace the radioligand [3H]pramipexole was tested |
J Med Chem 43: 756-62 (2000)
BindingDB Entry DOI: 10.7270/Q27W6CXP |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| DrugBank Article PubMed
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Displacement of [3H]-quinpirole from Dopamine receptor D2 |
J Med Chem 39: 4421-9 (1996)
Article DOI: 10.1021/jm960350p BindingDB Entry DOI: 10.7270/Q21G0KCQ |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
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| DrugBank PubMed
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Displacement of [3H]-quinpirole from human dopamine D2A receptors expressed in LtK cells |
Bioorg Med Chem Lett 9: 2167-72 (1999)
BindingDB Entry DOI: 10.7270/Q2CF9P97 |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
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| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Amsterdam
Curated by ChEMBL
| Assay Description Displacement of [3H]-raclopride from high-affinity state of human dopamine D2L receptor (443 amino acids) expressed in LTK deficient mouse fibroblast... |
J Med Chem 57: 391-410 (2014)
Article DOI: 10.1021/jm401384w BindingDB Entry DOI: 10.7270/Q2WS8VQD |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Rattus norvegicus (rat)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
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| Article PubMed
| 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toronto
Curated by PDSP Ki Database
| |
Nature 350: 610-4 (1991)
Article DOI: 10.1038/350610a0 BindingDB Entry DOI: 10.7270/Q24T6GVD |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
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| 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NeuroSearch Sweden AB
Curated by ChEMBL
| Assay Description Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cells |
J Med Chem 53: 2510-20 (2010)
Article DOI: 10.1021/jm901689v BindingDB Entry DOI: 10.7270/Q2NG4RKK |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
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| Article PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program
Curated by ChEMBL
| Assay Description Displacement of [3H]-(R)-(+)-7-OH-DPAT from human dopamine D3 receptor expressed in HEK293 cell membranes after 90 mins by micro beta scintillation c... |
J Med Chem 60: 2890-2907 (2017)
Article DOI: 10.1021/acs.jmedchem.6b01875 BindingDB Entry DOI: 10.7270/Q28P62SD |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
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| DrugBank Article PubMed
| 6.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich Alexander University
Curated by ChEMBL
| Assay Description Displacement of [3H]spiperone from human D4 receptor expressed in CHO cells |
J Med Chem 51: 6829-38 (2008)
Article DOI: 10.1021/jm800895v BindingDB Entry DOI: 10.7270/Q2SN08TC |
More data for this Ligand-Target Pair | |
D(1A) dopamine receptor
(BOVINE) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
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| PDB PubMed
| 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich-Alexander University
Curated by ChEMBL
| Assay Description Binding Affinity was tested on High Affinity Site of Bovine Dopamine receptor D1. Tested for ability to displace the radioligand [3H]-SCH- 23390 |
J Med Chem 43: 756-62 (2000)
BindingDB Entry DOI: 10.7270/Q27W6CXP |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Dopamine receptor D4
(CANINE) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | UniProtKB/TrEMBL
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| Article PubMed
| 7.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toronto
Curated by PDSP Ki Database
| |
Nature 350: 610-4 (1991)
Article DOI: 10.1038/350610a0 BindingDB Entry DOI: 10.7270/Q24T6GVD |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
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| Article PubMed
| 7.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description Displacement of [3H]7-OH-DPAT from human D3 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counter |
J Med Chem 59: 2973-88 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01612 BindingDB Entry DOI: 10.7270/Q2708393 |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
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| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Monash University (Parkville Campus)
Curated by ChEMBL
| Assay Description Displacement of [3H]-NPA from dopamine D2L receptor (unknown origin) expressed in CHO cell membranes |
J Med Chem 56: 9199-221 (2013)
Article DOI: 10.1021/jm401318w BindingDB Entry DOI: 10.7270/Q2RF5WGV |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
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| DrugBank Article PubMed
| 8.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University College of Physicians and Surgeons
Curated by ChEMBL
| Assay Description Displacement of [3H]7-OH-DPAT from human D2 receptor transfected in HEK293 cells measured after 60 mins by liquid scintillation counter |
J Med Chem 59: 2973-88 (2016)
Article DOI: 10.1021/acs.jmedchem.5b01612 BindingDB Entry DOI: 10.7270/Q2708393 |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(BOVINE) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
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| PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich-Alexander University
Curated by ChEMBL
| Assay Description Binding Affinity was tested on high Affinity Site of Bovine Dopamine D2 Receptor. Tested for ability to displace the radioligand [3H]spiperone was te... |
J Med Chem 43: 756-62 (2000)
BindingDB Entry DOI: 10.7270/Q27W6CXP |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Rattus norvegicus (Rat)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | KEGG
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| Article PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita' di Siena
Curated by ChEMBL
| Assay Description Binding affinity which represents concentration giving half-maximal inhibition of [3H]7-OH-DPAT binding to Dopamine receptor D3 in rat tissue homogen... |
J Med Chem 41: 3763-72 (1998)
Article DOI: 10.1021/jm9706832 BindingDB Entry DOI: 10.7270/Q2JH3MVJ |
More data for this Ligand-Target Pair | |
D(1A) dopamine receptor
(BOVINE) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
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| 11.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by PDSP Ki Database
| |
Mol Pharmacol 12: 800-12 (1976)
BindingDB Entry DOI: 10.7270/Q22B8WH6 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
UniProtKB/SwissProt
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| Article PubMed
| 13.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Displacement of [3H]-raclopride from Dopamine receptor D3 |
J Med Chem 39: 4421-9 (1996)
Article DOI: 10.1021/jm960350p BindingDB Entry DOI: 10.7270/Q21G0KCQ |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(BOVINE) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
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| Article PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Pisa
Curated by ChEMBL
| Assay Description Inhibition of [3H]YM-09151-2 binding to bovine retina membrane Dopamine receptor D2, high affinity site |
J Med Chem 41: 4933-8 (1999)
Article DOI: 10.1021/jm9708700 BindingDB Entry DOI: 10.7270/Q2FJ2HGD |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
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| Article PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tartu
Curated by ChEMBL
| Assay Description Displacement of [3H]raclopride from human D3 receptor expressed in HEK293 cells |
Eur J Med Chem 55: 255-61 (2012)
Article DOI: 10.1016/j.ejmech.2012.07.025 BindingDB Entry DOI: 10.7270/Q2VT1T56 |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Rattus norvegicus (rat)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
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| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In vitro affinity against Dopamine receptor D2 using [3H]DP-5,6-ADTN radioligand in rat striatal homogenate. |
J Med Chem 29: 1889-95 (1986)
BindingDB Entry DOI: 10.7270/Q2ZC83F6 |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
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| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program
Curated by ChEMBL
| Assay Description Displacement of [3H]-(R)-(+)-7-OH-DPAT from human dopamine D2 receptor expressed in HEK293 cell membranes after 90 mins by micro beta scintillation c... |
J Med Chem 60: 2890-2907 (2017)
Article DOI: 10.1021/acs.jmedchem.6b01875 BindingDB Entry DOI: 10.7270/Q28P62SD |
More data for this Ligand-Target Pair | |
D(1A) dopamine receptor
(BOVINE) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
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| 16.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by PDSP Ki Database
| |
Mol Pharmacol 12: 800-12 (1976)
BindingDB Entry DOI: 10.7270/Q22B8WH6 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
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| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich-Alexander University
Curated by ChEMBL
| Assay Description Binding Affinity on High Affinity Site of Dopamine receptor D2S |
J Med Chem 43: 756-62 (2000)
BindingDB Entry DOI: 10.7270/Q27W6CXP |
More data for this Ligand-Target Pair | |
D(1A) dopamine receptor
(BOVINE) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
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| PDB PubMed
| 17.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by PDSP Ki Database
| |
Mol Pharmacol 12: 800-12 (1976)
BindingDB Entry DOI: 10.7270/Q22B8WH6 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
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| Article PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck
Curated by ChEMBL
| Assay Description Displacement of [3H]YM-09151-2 from human dopamine D3 receptor expressed in CHOp cells |
J Med Chem 55: 10302-6 (2012)
Article DOI: 10.1021/jm301258w BindingDB Entry DOI: 10.7270/Q24X58ZX |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich-Alexander University
Curated by ChEMBL
| Assay Description Binding affinity on High Affinity Site of Dopamine receptor D2L |
J Med Chem 43: 756-62 (2000)
BindingDB Entry DOI: 10.7270/Q27W6CXP |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
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| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SRI International
Curated by PDSP Ki Database
| |
NIDA Res Monogr 178: 440-66 (1998)
BindingDB Entry DOI: 10.7270/Q23J3BH2 |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
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| Article PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich Alexander University
Curated by ChEMBL
| Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells |
Bioorg Med Chem 21: 1680-4 (2013)
Article DOI: 10.1016/j.bmc.2013.01.065 BindingDB Entry DOI: 10.7270/Q21Z45SG |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
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| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Amsterdam
Curated by ChEMBL
| Assay Description Displacement of [3H]-iodosulpiride from cloned human dopamine D2S receptor expressed in CHO cells |
J Med Chem 57: 391-410 (2014)
Article DOI: 10.1021/jm401384w BindingDB Entry DOI: 10.7270/Q2WS8VQD |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
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| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
U. 109
Curated by PDSP Ki Database
| |
Arzneimittelforschung 42: 224-30 (1992)
BindingDB Entry DOI: 10.7270/Q2QR4VK6 |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Rattus norvegicus (Rat)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | KEGG
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| Article PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
U. 109
Curated by PDSP Ki Database
| |
Nature 347: 146-51 (1990)
Article DOI: 10.1038/347146a0 BindingDB Entry DOI: 10.7270/Q2CC0Z5N |
More data for this Ligand-Target Pair | |
Dopamine receptor D4
(CANINE) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | UniProtKB/TrEMBL
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| Article PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Toronto
Curated by PDSP Ki Database
| |
Nature 350: 610-4 (1991)
Article DOI: 10.1038/350610a0 BindingDB Entry DOI: 10.7270/Q24T6GVD |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
UniProtKB/SwissProt
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| 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neuroscience Research Centre
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 268: 417-26 (1994)
BindingDB Entry DOI: 10.7270/Q2C827SR |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
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| Article PubMed
| 33.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Croissy-sur-Seine Paris
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 361: 569-72 (2000)
Article DOI: 10.1007/s002100000217 BindingDB Entry DOI: 10.7270/Q2GB22M2 |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich-Alexander University
Curated by ChEMBL
| Assay Description Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D2S |
J Med Chem 43: 756-62 (2000)
BindingDB Entry DOI: 10.7270/Q27W6CXP |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(BOVINE) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
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| 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by ChEMBL
| Assay Description High binding affinity of the compound for dopamine D-2 receptor from bovine anterior pitutary membrane, using radioligand [3H]-spiroperidol |
J Med Chem 32: 961-8 (1989)
BindingDB Entry DOI: 10.7270/Q2CN72WQ |
More data for this Ligand-Target Pair | |
D(1A) dopamine receptor
(BOVINE) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
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| 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich-Alexander University
Curated by ChEMBL
| Assay Description Binding Affinity was tested on relative proportion of High Affinity Site of Bovine dopamine receptor D1. Tested for ability to displace the radioliga... |
J Med Chem 43: 756-62 (2000)
BindingDB Entry DOI: 10.7270/Q27W6CXP |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | Reactome pathway KEGG
UniProtKB/SwissProt
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| Article PubMed
| 38.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIH
Curated by PDSP Ki Database
| |
Synapse 39: 32-41 (2001)
Article DOI: 10.1002/1098-2396(20010101)39:1 BindingDB Entry DOI: 10.7270/Q2NV9GT3 |
More data for this Ligand-Target Pair | |
Norepinephrine transporter
(RAT) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | UniProtKB/TrEMBL
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| Article PubMed
| 40.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NIH
Curated by PDSP Ki Database
| |
Synapse 39: 32-41 (2001)
Article DOI: 10.1002/1098-2396(20010101)39:1 BindingDB Entry DOI: 10.7270/Q2NV9GT3 |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich-Alexander University
Curated by ChEMBL
| Assay Description Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D2L |
J Med Chem 43: 756-62 (2000)
BindingDB Entry DOI: 10.7270/Q27W6CXP |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
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| 42.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 181-91 (1997)
BindingDB Entry DOI: 10.7270/Q29K48SD |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
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| 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich-Alexander University
Curated by ChEMBL
| Assay Description Displacement of [3H]spiperone from human D2S receptor expressed in CHO cells |
Bioorg Med Chem 24: 2641-53 (2016)
Article DOI: 10.1016/j.bmc.2016.04.028 BindingDB Entry DOI: 10.7270/Q2ZC84S3 |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Rattus norvegicus (Rat)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | KEGG
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| 49 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania
Curated by ChEMBL
| Assay Description Tested for binding affinity against dopamine receptor D3 expressed in Sf9 cells. |
J Med Chem 36: 1499-500 (1993)
BindingDB Entry DOI: 10.7270/Q2F47PRT |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
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| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich-Alexander University
Curated by ChEMBL
| Assay Description Binding Affinity was tested on the high affinity site of Dopamine receptor D3 |
J Med Chem 43: 756-62 (2000)
BindingDB Entry DOI: 10.7270/Q27W6CXP |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(BOVINE) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
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| 51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich-Alexander University
Curated by ChEMBL
| Assay Description Binding Affinity was tested on relative proportion of high Affinity Site of Bovine dopamine receptor D2. Tested for ability to displace the radioliga... |
J Med Chem 43: 756-62 (2000)
BindingDB Entry DOI: 10.7270/Q27W6CXP |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Rattus norvegicus (rat)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
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| 51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
DuPont Merck Pharmaceutical Company
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 262: 929-35 (1992)
BindingDB Entry DOI: 10.7270/Q2RR1WQK |
More data for this Ligand-Target Pair | |
D(1A) dopamine receptor
(BOVINE) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
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| 51.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nebraska
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 253: 214-20 (1990)
BindingDB Entry DOI: 10.7270/Q2PN9447 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
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| 52 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Friedrich-Alexander University
Curated by ChEMBL
| Assay Description Binding Affinity was tested on relative proportion of High Affinity Site of Dopamine receptor D3 |
J Med Chem 43: 756-62 (2000)
BindingDB Entry DOI: 10.7270/Q27W6CXP |
More data for this Ligand-Target Pair | |
D(3) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
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| 55.0 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Croissy-sur-Seine Paris
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 361: 569-72 (2000)
Article DOI: 10.1007/s002100000217 BindingDB Entry DOI: 10.7270/Q2GB22M2 |
More data for this Ligand-Target Pair | |