Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM83436 (2-(3,4-dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-(1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 0.0300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by PDSP Ki Database | Mol Pharmacol 45: 330-4 (1994) Article DOI: 10.1016/j.bioorg.2015.02.008 BindingDB Entry DOI: 10.7270/Q21Z42X1 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Mus musculus (Mouse)) | BDBM83436 (2-(3,4-dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-(1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Farmaceutici S.p.A. Curated by ChEMBL | Assay Description Evaluated for the binding affinity at kappa receptor | J Med Chem 37: 3482-91 (1994) BindingDB Entry DOI: 10.7270/Q2W37VB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM83436 (2-(3,4-dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-(1...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 1.53 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Research Foundation Curated by PDSP Ki Database | Psychopharmacology (Berl) 124: 57-73 (1996) Article DOI: 10.1007/bf02245606 BindingDB Entry DOI: 10.7270/Q2610XV6 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM83436 (2-(3,4-dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-(1...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PubMed | 8.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Taiwan University Curated by ChEMBL | Assay Description Binding affinity against opioid receptor kappa from guinea pig brain membranes using [3H]ethylketocyclazocine as radioligand | J Med Chem 35: 2243-7 (1992) BindingDB Entry DOI: 10.7270/Q20K296N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM83436 (2-(3,4-dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-(1...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Binding affinity for the Opioid receptor kappa 1 | J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM83436 (2-(3,4-dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-(1...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by PDSP Ki Database | Mol Pharmacol 45: 330-4 (1994) Article DOI: 10.1016/j.bioorg.2015.02.008 BindingDB Entry DOI: 10.7270/Q21Z42X1 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (GUINEA PIG) | BDBM83436 (2-(3,4-dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-(1...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PubMed | 252 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Taiwan University Curated by ChEMBL | Assay Description Binding affinity against opioid receptor mu from guinea pig brain membranes using [3H]naloxone as radioligand | J Med Chem 35: 2243-7 (1992) BindingDB Entry DOI: 10.7270/Q20K296N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM83436 (2-(3,4-dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-(1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by PDSP Ki Database | Mol Pharmacol 45: 330-4 (1994) Article DOI: 10.1016/j.bioorg.2015.02.008 BindingDB Entry DOI: 10.7270/Q21Z42X1 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (GUINEA PIG) | BDBM83436 (2-(3,4-dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-(1...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PubMed | 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Research Unit Curated by ChEMBL | Assay Description Binding affinity for the Opioid receptor mu 1 | J Med Chem 31: 831-6 (1988) BindingDB Entry DOI: 10.7270/Q2R78FSK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM83436 (2-(3,4-dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-(1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PubMed | 9.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Taiwan University Curated by ChEMBL | Assay Description Binding affinity against opioid receptor delta from guinea pig brain membranes using [3H]DADLE as radioligand | J Med Chem 35: 2243-7 (1992) BindingDB Entry DOI: 10.7270/Q20K296N | |||||||||||
More data for this Ligand-Target Pair |