Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Chymotrypsin-like elastase family member 2A (Sus scrofa) | BDBM50282868 (1,1-Dioxo-2-(1-phenyl-1H-tetrazol-5-ylsulfanylmeth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 26 | n/a | n/a | n/a | n/a | n/a | 130 | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Apparent binding constant Ki=Kon/Koff | Bioorg Med Chem Lett 6: 2941-2946 (1996) Article DOI: 10.1016/S0960-894X(96)00553-7 BindingDB Entry DOI: 10.7270/Q2KP825W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM50282868 (1,1-Dioxo-2-(1-phenyl-1H-tetrazol-5-ylsulfanylmeth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | n/a | n/a | n/a | 0.0000700 | 1.00E+4 | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Evaluated for inhibitory activity against Human leukocyte elastase (HLE) | Bioorg Med Chem Lett 5: 331-336 (1995) Article DOI: 10.1016/0960-894X(95)00030-W BindingDB Entry DOI: 10.7270/Q2SX6D60 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM50282868 (1,1-Dioxo-2-(1-phenyl-1H-tetrazol-5-ylsulfanylmeth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.700 | n/a | n/a | n/a | n/a | n/a | 1.00E+5 | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Apparent binding constant Ki=Kon/Koff | Bioorg Med Chem Lett 6: 2941-2946 (1996) Article DOI: 10.1016/S0960-894X(96)00553-7 BindingDB Entry DOI: 10.7270/Q2KP825W | |||||||||||
More data for this Ligand-Target Pair |