Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50016982'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50016982 (CHEMBL3287027) Show SMILES NC(=O)[C@@]12CC3CC(C[C@](C3)(C1)NC(=O)CN1CCCN(c3c(Cl)cc(Cl)cc3Cl)S1(=O)=O)C2 |r,TLB:33:3:8.7.6:10,THB:33:7:10:11.3.4,4:3:8:6.5.10,4:5:8:11.33.3,1:3:8:6.5.10,1:3:8.7.6:10| Show InChI InChI=1S/C22H27Cl3N4O4S/c23-15-5-16(24)19(17(25)6-15)29-3-1-2-28(34(29,32)33)11-18(30)27-22-9-13-4-14(10-22)8-21(7-13,12-22)20(26)31/h5-6,13-14H,1-4,7-12H2,(H2,26,31)(H,27,30)/t13?,14?,21-,22-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1				J Med Chem 57: 4466-86 (2014) Article DOI: 10.1021/jm4014746 BindingDB Entry DOI: 10.7270/Q280546B
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50016982 (CHEMBL3287027) Show SMILES NC(=O)[C@@]12CC3CC(C[C@](C3)(C1)NC(=O)CN1CCCN(c3c(Cl)cc(Cl)cc3Cl)S1(=O)=O)C2 |r,TLB:33:3:8.7.6:10,THB:33:7:10:11.3.4,4:3:8:6.5.10,4:5:8:11.33.3,1:3:8:6.5.10,1:3:8.7.6:10| Show InChI InChI=1S/C22H27Cl3N4O4S/c23-15-5-16(24)19(17(25)6-15)29-3-1-2-28(34(29,32)33)11-18(30)27-22-9-13-4-14(10-22)8-21(7-13,12-22)20(26)31/h5-6,13-14H,1-4,7-12H2,(H2,26,31)(H,27,30)/t13?,14?,21-,22-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD1				J Med Chem 57: 4466-86 (2014) Article DOI: 10.1021/jm4014746 BindingDB Entry DOI: 10.7270/Q280546B
					More data for this Ligand-Target Pair