Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50016983'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50016983 (CHEMBL3220543) Show SMILES [H][C@@]12CN(C[C@]1([H])[C@H]2C(O)=O)c1ccc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(SC)n1 |r,TLB:17:18:21.20.25:23,THB:19:20:23:27.18.26,19:18:21.20.25:23,26:18:21:25.24.23,26:24:21:27.19.18| Show InChI InChI=1S/C23H29N3O3S/c1-30-21-15(2-3-18(24-21)26-10-16-17(11-26)19(16)22(28)29)20(27)25-23-7-12-4-13(8-23)6-14(5-12)9-23/h2-3,12-14,16-17,19H,4-11H2,1H3,(H,25,27)(H,28,29)/t12?,13?,14?,16-,17+,19+,23?	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of N-terminal His-tagged full length human 11beta-HSD1 assessed as inhibition of cortisone to cortisol conversion preincubated for 25 mins...				J Med Chem 57: 4466-86 (2014) Article DOI: 10.1021/jm4014746 BindingDB Entry DOI: 10.7270/Q280546B
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Rattus norvegicus (rat))	BDBM50016983 (CHEMBL3220543) Show SMILES [H][C@@]12CN(C[C@]1([H])[C@H]2C(O)=O)c1ccc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(SC)n1 |r,TLB:17:18:21.20.25:23,THB:19:20:23:27.18.26,19:18:21.20.25:23,26:18:21:25.24.23,26:24:21:27.19.18| Show InChI InChI=1S/C23H29N3O3S/c1-30-21-15(2-3-18(24-21)26-10-16-17(11-26)19(16)22(28)29)20(27)25-23-7-12-4-13(8-23)6-14(5-12)9-23/h2-3,12-14,16-17,19H,4-11H2,1H3,(H,25,27)(H,28,29)/t12?,13?,14?,16-,17+,19+,23?	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of N-terminal His-tagged full length rat 11beta-HSD1 assessed as inhibition of cortisone to cortisol conversion preincubated for 25 mins m...				J Med Chem 57: 4466-86 (2014) Article DOI: 10.1021/jm4014746 BindingDB Entry DOI: 10.7270/Q280546B
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50016983 (CHEMBL3220543) Show SMILES [H][C@@]12CN(C[C@]1([H])[C@H]2C(O)=O)c1ccc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(SC)n1 |r,TLB:17:18:21.20.25:23,THB:19:20:23:27.18.26,19:18:21.20.25:23,26:18:21:25.24.23,26:24:21:27.19.18| Show InChI InChI=1S/C23H29N3O3S/c1-30-21-15(2-3-18(24-21)26-10-16-17(11-26)19(16)22(28)29)20(27)25-23-7-12-4-13(8-23)6-14(5-12)9-23/h2-3,12-14,16-17,19H,4-11H2,1H3,(H,25,27)(H,28,29)/t12?,13?,14?,16-,17+,19+,23?	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of N-terminal His-tagged full length mouse 11beta-HSD1 assessed as inhibition of cortisone to cortisol conversion preincubated for 25 mins...				J Med Chem 57: 4466-86 (2014) Article DOI: 10.1021/jm4014746 BindingDB Entry DOI: 10.7270/Q280546B
					More data for this Ligand-Target Pair