Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50224214'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50224214 (2-(1H-indazol-5-ylamino)-5-isopropylthiazol-4(5H)-...) Show SMILES CC(C)c1sc(Nc2ccc3n[nH]cc3c2)nc1O Show InChI InChI=1S/C13H14N4OS/c1-7(2)11-12(18)16-13(19-11)15-9-3-4-10-8(5-9)6-14-17-10/h3-7,18H,1-2H3,(H,14,17)(H,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human 11betaHSD1 by SPA				Bioorg Med Chem Lett 17: 6056-61 (2007) Article DOI: 10.1016/j.bmcl.2007.09.070 BindingDB Entry DOI: 10.7270/Q2X34X6D
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50224214 (2-(1H-indazol-5-ylamino)-5-isopropylthiazol-4(5H)-...) Show SMILES CC(C)c1sc(Nc2ccc3n[nH]cc3c2)nc1O Show InChI InChI=1S/C13H14N4OS/c1-7(2)11-12(18)16-13(19-11)15-9-3-4-10-8(5-9)6-14-17-10/h3-7,18H,1-2H3,(H,14,17)(H,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human 11betaHSD1 in CHO cells assessed as conversion of cortisone to cortisol				Bioorg Med Chem Lett 17: 6056-61 (2007) Article DOI: 10.1016/j.bmcl.2007.09.070 BindingDB Entry DOI: 10.7270/Q2X34X6D
					More data for this Ligand-Target Pair