Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human)) | BDBM50224225 (5-isopropyl-2-(2-methylbenzo[d]thiazol-5-ylamino)t...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 510 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Inhibition of human 11betaHSD1 by SPA | Bioorg Med Chem Lett 17: 6056-61 (2007) Article DOI: 10.1016/j.bmcl.2007.09.070 BindingDB Entry DOI: 10.7270/Q2X34X6D | |||||||||||
More data for this Ligand-Target Pair |