Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50239625'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50239625 (CHEMBL4080314) Show SMILES Cc1ccc(cc1)C1(CC(=O)N2CC(O)C2)C2CC3CC1CC(C2)C3O |TLB:19:18:7.20.21:23,8:7:23:17.18.24,4:7:17.19.18:21.22.23,THB:25:24:7.20.21:23,19:20:23:17.18.24,24:18:7:21.22.23,24:22:7:17.19.18,8:7:17.19.18:21.22.23,4:7:23:17.18.24,(11.65,-14.63,;11.66,-13.08,;10.33,-12.3,;10.35,-10.76,;11.69,-10.01,;13.01,-10.79,;13,-12.32,;11.71,-8.47,;10.56,-7.44,;9.1,-7.91,;8.77,-9.42,;7.95,-6.88,;7.88,-5.34,;6.34,-5.42,;5.19,-4.39,;6.42,-6.96,;12.91,-7.19,;14.23,-7.69,;15.63,-7.34,;14.62,-8.62,;13.2,-8.05,;13.2,-6.47,;14.24,-5.23,;12.9,-5.71,;15.65,-5.81,;16.93,-4.97,)| Show InChI InChI=1S/C22H29NO3/c1-13-2-4-16(5-3-13)22(10-20(25)23-11-19(24)12-23)17-6-14-7-18(22)9-15(8-17)21(14)26/h2-5,14-15,17-19,21,24,26H,6-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of 11beta-HSD1 in human microsomes using [3H]cortisone as substrate preincubated for 10 mins followed by substrate addition measured after...				J Med Chem 60: 4932-4948 (2017) Article DOI: 10.1021/acs.jmedchem.7b00211 BindingDB Entry DOI: 10.7270/Q2DV1N23
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50239625 (CHEMBL4080314) Show SMILES Cc1ccc(cc1)C1(CC(=O)N2CC(O)C2)C2CC3CC1CC(C2)C3O |TLB:19:18:7.20.21:23,8:7:23:17.18.24,4:7:17.19.18:21.22.23,THB:25:24:7.20.21:23,19:20:23:17.18.24,24:18:7:21.22.23,24:22:7:17.19.18,8:7:17.19.18:21.22.23,4:7:23:17.18.24,(11.65,-14.63,;11.66,-13.08,;10.33,-12.3,;10.35,-10.76,;11.69,-10.01,;13.01,-10.79,;13,-12.32,;11.71,-8.47,;10.56,-7.44,;9.1,-7.91,;8.77,-9.42,;7.95,-6.88,;7.88,-5.34,;6.34,-5.42,;5.19,-4.39,;6.42,-6.96,;12.91,-7.19,;14.23,-7.69,;15.63,-7.34,;14.62,-8.62,;13.2,-8.05,;13.2,-6.47,;14.24,-5.23,;12.9,-5.71,;15.65,-5.81,;16.93,-4.97,)| Show InChI InChI=1S/C22H29NO3/c1-13-2-4-16(5-3-13)22(10-20(25)23-11-19(24)12-23)17-6-14-7-18(22)9-15(8-17)21(14)26/h2-5,14-15,17-19,21,24,26H,6-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD1				J Med Chem 60: 4932-4948 (2017) Article DOI: 10.1021/acs.jmedchem.7b00211 BindingDB Entry DOI: 10.7270/Q2DV1N23
					More data for this Ligand-Target Pair