Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50306431'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50306431 (2-[(3R)-1'-[(adamantan-2-yl)carbamoyl]-7-bromo-2,3...) Show SMILES OC(=O)C[C@H]1CC2(CCN(CC2)C(=O)NC2C3CC4CC(C3)CC2C4)c2c1cccc2Br |r,TLB:21:20:24:17.16.15,21:16:19.20.22:24,THB:15:16:19:22.23.24,15:23:19:17.21.16,14:15:19.20.22:24| Show InChI InChI=1S/C26H33BrN2O3/c27-21-3-1-2-20-19(13-22(30)31)14-26(23(20)21)4-6-29(7-5-26)25(32)28-24-17-9-15-8-16(11-17)12-18(24)10-15/h1-3,15-19,24H,4-14H2,(H,28,32)(H,30,31)/t15?,16?,17?,18?,19-,24?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human recombinant 11beta-HSD1 expressed in CHO cells assessed as conversion of [3H]cortisone to [3H]cortisol by SPA				Bioorg Med Chem Lett 20: 881-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.082 BindingDB Entry DOI: 10.7270/Q2KK9BWZ
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50306431 (2-[(3R)-1'-[(adamantan-2-yl)carbamoyl]-7-bromo-2,3...) Show SMILES OC(=O)C[C@H]1CC2(CCN(CC2)C(=O)NC2C3CC4CC(C3)CC2C4)c2c1cccc2Br |r,TLB:21:20:24:17.16.15,21:16:19.20.22:24,THB:15:16:19:22.23.24,15:23:19:17.21.16,14:15:19.20.22:24| Show InChI InChI=1S/C26H33BrN2O3/c27-21-3-1-2-20-19(13-22(30)31)14-26(23(20)21)4-6-29(7-5-26)25(32)28-24-17-9-15-8-16(11-17)12-18(24)10-15/h1-3,15-19,24H,4-14H2,(H,28,32)(H,30,31)/t15?,16?,17?,18?,19-,24?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD-1				Bioorg Med Chem Lett 21: 6699-704 (2011) Article DOI: 10.1016/j.bmcl.2011.09.055 BindingDB Entry DOI: 10.7270/Q2Q240NV
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50306431 (2-[(3R)-1'-[(adamantan-2-yl)carbamoyl]-7-bromo-2,3...) Show SMILES OC(=O)C[C@H]1CC2(CCN(CC2)C(=O)NC2C3CC4CC(C3)CC2C4)c2c1cccc2Br |r,TLB:21:20:24:17.16.15,21:16:19.20.22:24,THB:15:16:19:22.23.24,15:23:19:17.21.16,14:15:19.20.22:24| Show InChI InChI=1S/C26H33BrN2O3/c27-21-3-1-2-20-19(13-22(30)31)14-26(23(20)21)4-6-29(7-5-26)25(32)28-24-17-9-15-8-16(11-17)12-18(24)10-15/h1-3,15-19,24H,4-14H2,(H,28,32)(H,30,31)/t15?,16?,17?,18?,19-,24?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of 11beta-HSD1 in human adipocytes assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by SPA				Bioorg Med Chem Lett 20: 881-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.082 BindingDB Entry DOI: 10.7270/Q2KK9BWZ
					More data for this Ligand-Target Pair