Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50317225'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50317225 ((2R)-N-(adamantan-2-yl)-1-[(1-hydroxycyclopentyl)m...) Show SMILES OC1(CN2CCC[C@@H]2C(=O)NC2C3CC4CC(C3)CC2C4)CCCC1 |r,wU:7.8,TLB:17:16:20:13.12.11,17:12:15.16.18:20,THB:10:11:15.16.18:20,11:12:15:18.19.20,11:19:15:13.17.12,(25.94,3.33,;26.11,4.86,;24.57,4.88,;23.67,3.63,;22.13,3.6,;21.67,2.14,;22.91,1.24,;24.13,2.22,;25.64,1.7,;26.99,2.46,;25.61,.16,;24.26,-.58,;24.25,-2.12,;22.86,-2.47,;21.51,-1.98,;20.31,-3.26,;21.82,-2.83,;23.24,-3.4,;21.81,-1.25,;22.86,-0,;21.5,-.49,;25.97,6.39,;27.38,7.01,;28.41,5.86,;27.63,4.53,)| Show InChI InChI=1S/C21H34N2O2/c24-20(18-4-3-7-23(18)13-21(25)5-1-2-6-21)22-19-16-9-14-8-15(11-16)12-17(19)10-14/h14-19,25H,1-13H2,(H,22,24)/t14?,15?,16?,17?,18-,19?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research& Development Curated by ChEMBL					Assay Description Inhibition of mouse 11-beta-HSD1				Bioorg Med Chem Lett 20: 2897-902 (2010) Article DOI: 10.1016/j.bmcl.2010.03.032 BindingDB Entry DOI: 10.7270/Q2NV9JDJ
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50317225 ((2R)-N-(adamantan-2-yl)-1-[(1-hydroxycyclopentyl)m...) Show SMILES OC1(CN2CCC[C@@H]2C(=O)NC2C3CC4CC(C3)CC2C4)CCCC1 |r,wU:7.8,TLB:17:16:20:13.12.11,17:12:15.16.18:20,THB:10:11:15.16.18:20,11:12:15:18.19.20,11:19:15:13.17.12,(25.94,3.33,;26.11,4.86,;24.57,4.88,;23.67,3.63,;22.13,3.6,;21.67,2.14,;22.91,1.24,;24.13,2.22,;25.64,1.7,;26.99,2.46,;25.61,.16,;24.26,-.58,;24.25,-2.12,;22.86,-2.47,;21.51,-1.98,;20.31,-3.26,;21.82,-2.83,;23.24,-3.4,;21.81,-1.25,;22.86,-0,;21.5,-.49,;25.97,6.39,;27.38,7.01,;28.41,5.86,;27.63,4.53,)| Show InChI InChI=1S/C21H34N2O2/c24-20(18-4-3-7-23(18)13-21(25)5-1-2-6-21)22-19-16-9-14-8-15(11-16)12-17(19)10-14/h14-19,25H,1-13H2,(H,22,24)/t14?,15?,16?,17?,18-,19?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.340	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research& Development Curated by ChEMBL					Assay Description Inhibition of human 11-beta-HSD1 expressed in HEK293 cells co-transfected with GRE-luciferase after 6 hrs by luciferase reporter gene assay				Bioorg Med Chem Lett 20: 2897-902 (2010) Article DOI: 10.1016/j.bmcl.2010.03.032 BindingDB Entry DOI: 10.7270/Q2NV9JDJ
					More data for this Ligand-Target Pair