Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50331361'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50331361 ((S)-3'-chloro-4'-(4-(1,1,1-trifluoro-2-hydroxyprop...) Show SMILES C[C@](O)(c1ccc(cc1)S(=O)(=O)c1ccc(cc1Cl)-c1ccc(cc1)C#N)C(F)(F)F |r| Show InChI InChI=1S/C22H15ClF3NO3S/c1-21(28,22(24,25)26)17-7-9-18(10-8-17)31(29,30)20-11-6-16(12-19(20)23)15-4-2-14(13-27)3-5-15/h2-12,28H,1H3/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 by scintillation proximity assay				Bioorg Med Chem Lett 20: 7071-5 (2010) Article DOI: 10.1016/j.bmcl.2010.09.097 BindingDB Entry DOI: 10.7270/Q21G0MHX
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50331361 ((S)-3'-chloro-4'-(4-(1,1,1-trifluoro-2-hydroxyprop...) Show SMILES C[C@](O)(c1ccc(cc1)S(=O)(=O)c1ccc(cc1Cl)-c1ccc(cc1)C#N)C(F)(F)F |r| Show InChI InChI=1S/C22H15ClF3NO3S/c1-21(28,22(24,25)26)17-7-9-18(10-8-17)31(29,30)20-11-6-16(12-19(20)23)15-4-2-14(13-27)3-5-15/h2-12,28H,1H3/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 transfected in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 7071-5 (2010) Article DOI: 10.1016/j.bmcl.2010.09.097 BindingDB Entry DOI: 10.7270/Q21G0MHX
					More data for this Ligand-Target Pair