Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50400159'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50400159 (CHEMBL2179443) Show SMILES CC(C)Oc1nc(N[C@H]2CCOC2)ncc1C(=O)N[C@H]1C2CC3CC1C[C@](O)(C3)C2 |r,wU:19.20,8.7,wD:26.29,TLB:27:26:19:23.22.21,18:19:29.25.26:23.22.21,18:19:21:29.26.28,THB:27:26:19.24.23:21,28:26:19:23.22.21,28:22:19:29.25.26,25:24:21:29.26.28,25:26:19.24.23:21,(27.91,-54.7,;26.58,-53.93,;25.24,-54.71,;26.57,-52.39,;25.24,-51.63,;23.9,-52.4,;22.57,-51.63,;21.23,-52.4,;19.9,-51.63,;18.49,-52.26,;17.46,-51.11,;18.23,-49.78,;19.74,-50.1,;22.57,-50.08,;23.9,-49.31,;25.23,-50.08,;26.56,-49.3,;26.56,-47.76,;27.9,-50.07,;29.23,-49.29,;29.22,-47.55,;28.19,-46.47,;28.84,-45.2,;28.86,-46.64,;30.03,-47.96,;31.44,-47.4,;31.3,-45.77,;32.83,-45.79,;30.26,-44.65,;30.52,-46.99,)| Show InChI InChI=1S/C22H32N4O4/c1-12(2)30-20-17(10-23-21(26-20)24-16-3-4-29-11-16)19(27)25-18-14-5-13-6-15(18)9-22(28,7-13)8-14/h10,12-16,18,28H,3-9,11H2,1-2H3,(H,25,27)(H,23,24,26)/t13?,14?,15?,16-,18-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 by HTRF assay				J Med Chem 55: 10652-61 (2012) Article DOI: 10.1021/jm3013163 BindingDB Entry DOI: 10.7270/Q2BG2Q4S
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50400159 (CHEMBL2179443) Show SMILES CC(C)Oc1nc(N[C@H]2CCOC2)ncc1C(=O)N[C@H]1C2CC3CC1C[C@](O)(C3)C2 |r,wU:19.20,8.7,wD:26.29,TLB:27:26:19:23.22.21,18:19:29.25.26:23.22.21,18:19:21:29.26.28,THB:27:26:19.24.23:21,28:26:19:23.22.21,28:22:19:29.25.26,25:24:21:29.26.28,25:26:19.24.23:21,(27.91,-54.7,;26.58,-53.93,;25.24,-54.71,;26.57,-52.39,;25.24,-51.63,;23.9,-52.4,;22.57,-51.63,;21.23,-52.4,;19.9,-51.63,;18.49,-52.26,;17.46,-51.11,;18.23,-49.78,;19.74,-50.1,;22.57,-50.08,;23.9,-49.31,;25.23,-50.08,;26.56,-49.3,;26.56,-47.76,;27.9,-50.07,;29.23,-49.29,;29.22,-47.55,;28.19,-46.47,;28.84,-45.2,;28.86,-46.64,;30.03,-47.96,;31.44,-47.4,;31.3,-45.77,;32.83,-45.79,;30.26,-44.65,;30.52,-46.99,)| Show InChI InChI=1S/C22H32N4O4/c1-12(2)30-20-17(10-23-21(26-20)24-16-3-4-29-11-16)19(27)25-18-14-5-13-6-15(18)9-22(28,7-13)8-14/h10,12-16,18,28H,3-9,11H2,1-2H3,(H,25,27)(H,23,24,26)/t13?,14?,15?,16-,18-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD1 by HTRF assay				J Med Chem 55: 10652-61 (2012) Article DOI: 10.1021/jm3013163 BindingDB Entry DOI: 10.7270/Q2BG2Q4S
					More data for this Ligand-Target Pair