Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '17-beta-hydroxysteroid dehydrogenase 14' and Ligand = 'BDBM50197842'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
17-beta-hydroxysteroid dehydrogenase 14 (Homo sapiens (Human))	BDBM50197842 (CHEMBL3922253) Show SMILES Oc1ccc(cc1F)-c1cccc(n1)C(=O)c1ccc(F)c(O)c1 Show InChI InChI=1S/C18H11F2NO3/c19-12-6-4-11(9-17(12)23)18(24)15-3-1-2-14(21-15)10-5-7-16(22)13(20)8-10/h1-9,22-23H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps University Marburg Curated by ChEMBL					Assay Description Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...				J Med Chem 59: 10719-10737 (2016) Article DOI: 10.1021/acs.jmedchem.6b01436 BindingDB Entry DOI: 10.7270/Q2KH0Q9S
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