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Found 1 hit Enz. Inhib. hit(s) with Target = '3-hydroxy-3-methylglutaryl-coenzyme A reductase' and Ligand = 'BDBM50321266'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
3-hydroxy-3-methylglutaryl-coenzyme A reductase


(Schizosaccharomyces pombe)		BDBM50321266
PNG
(4-chloro-N-(2-(2-methoxy-4-(prop-1-enyl)phenoxy)et...)
Show SMILES COc1cc(\C=C\C)ccc1OCCNC(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C19H20ClNO3/c1-3-4-14-5-10-17(18(13-14)23-2)24-12-11-21-19(22)15-6-8-16(20)9-7-15/h3-10,13H,11-12H2,1-2H3,(H,21,22)/b4-3+
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.29E+5n/an/an/an/an/an/a



Instituto Polit£cnico Nacional (IPN)

Curated by ChEMBL


Assay Description
Inhibition of Schizosaccharomyces pombe HMG-CoA reductase by spectrophotometry

Bioorg Med Chem 18: 4238-48 (2010)


Article DOI: 10.1016/j.bmc.2010.04.096
BindingDB Entry DOI: 10.7270/Q2KW5H0Z
More data for this
Ligand-Target Pair