Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '4-hydroxyphenylpyruvate dioxygenase' and Ligand = 'BDBM50024730'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50024730 (CHEMBL3342429) Show SMILES Cc1nn(C)c(O)c1C(=O)c1ccc2nc(C)n(-c3ccc(Cl)cc3C)c(=O)c2c1 |(40.51,-51.09,;39.34,-50.08,;37.84,-50.44,;37.05,-49.12,;35.52,-48.99,;38.05,-47.95,;37.7,-46.45,;39.48,-48.55,;40.79,-47.75,;40.76,-46.21,;42.14,-48.49,;42.17,-50.04,;43.52,-50.78,;44.83,-49.99,;46.19,-50.73,;47.52,-49.93,;48.87,-50.67,;47.48,-48.38,;48.8,-47.58,;50.14,-48.32,;51.46,-47.52,;51.42,-45.98,;52.74,-45.18,;50.06,-45.24,;48.75,-46.04,;47.4,-45.31,;46.12,-47.63,;46.08,-46.09,;44.8,-48.44,;43.45,-47.7,)| Show InChI InChI=1S/C22H19ClN4O3/c1-11-9-15(23)6-8-18(11)27-13(3)24-17-7-5-14(10-16(17)21(27)29)20(28)19-12(2)25-26(4)22(19)30/h5-10,30H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	177	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of purified His6-tagged recombinant human HPPD assessed as inhibition of maleylacetoacetate formation after 30 mins by UV/visible spectrop...				Bioorg Med Chem 22: 5194-211 (2014) Article DOI: 10.1016/j.bmc.2014.08.011 BindingDB Entry DOI: 10.7270/Q2DF6SRG
					More data for this Ligand-Target Pair