Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '4-hydroxyphenylpyruvate dioxygenase' and Ligand = 'BDBM50024732'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50024732 (CHEMBL3342427) Show SMILES Cc1nn(C)c(O)c1C(=O)c1ccc2nc(C)n(-c3ccc(F)cc3C)c(=O)c2c1 |(1.67,-50.37,;.51,-49.37,;-1,-49.72,;-1.79,-48.4,;-3.32,-48.28,;-.79,-47.23,;-1.15,-45.74,;.64,-47.83,;1.96,-47.04,;1.93,-45.5,;3.31,-47.78,;3.33,-49.32,;4.68,-50.07,;6,-49.27,;7.35,-50.02,;8.68,-49.21,;10.03,-49.95,;8.65,-47.66,;9.96,-46.86,;11.31,-47.61,;12.62,-46.81,;12.59,-45.27,;13.91,-44.47,;11.23,-44.53,;9.92,-45.33,;8.57,-44.59,;7.28,-46.91,;7.25,-45.37,;5.96,-47.72,;4.62,-46.99,)| Show InChI InChI=1S/C22H19FN4O3/c1-11-9-15(23)6-8-18(11)27-13(3)24-17-7-5-14(10-16(17)21(27)29)20(28)19-12(2)25-26(4)22(19)30/h5-10,30H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	219	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of purified His6-tagged recombinant human HPPD assessed as inhibition of maleylacetoacetate formation after 30 mins by UV/visible spectrop...				Bioorg Med Chem 22: 5194-211 (2014) Article DOI: 10.1016/j.bmc.2014.08.011 BindingDB Entry DOI: 10.7270/Q2DF6SRG
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