Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '4-hydroxyphenylpyruvate dioxygenase' and Ligand = 'BDBM50024747'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50024747 (CHEMBL3342412) Show SMILES Cc1nn(C)c(O)c1C(=O)c1ccc2nc(C)n(-c3ccccc3Cl)c(=O)c2c1 |(5.74,-6.55,;4.58,-5.55,;3.08,-5.9,;2.28,-4.58,;.75,-4.46,;3.28,-3.42,;2.93,-1.92,;4.71,-4.01,;6.03,-3.22,;6,-1.68,;7.38,-3.96,;7.4,-5.5,;8.75,-6.25,;10.07,-5.45,;11.42,-6.2,;12.75,-5.39,;14.1,-6.14,;12.71,-3.84,;14.03,-3.04,;13.99,-1.51,;15.3,-.71,;16.66,-1.45,;16.69,-2.99,;15.37,-3.79,;15.4,-5.33,;11.35,-3.09,;11.31,-1.55,;10.03,-3.9,;8.68,-3.17,)| Show InChI InChI=1S/C21H17ClN4O3/c1-11-18(21(29)25(3)24-11)19(27)13-8-9-16-14(10-13)20(28)26(12(2)23-16)17-7-5-4-6-15(17)22/h4-10,29H,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of purified His6-tagged recombinant human HPPD assessed as inhibition of maleylacetoacetate formation after 30 mins by UV/visible spectrop...				Bioorg Med Chem 22: 5194-211 (2014) Article DOI: 10.1016/j.bmc.2014.08.011 BindingDB Entry DOI: 10.7270/Q2DF6SRG
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