Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '4-hydroxyphenylpyruvate dioxygenase' and Ligand = 'BDBM50024753'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50024753 (CHEMBL3343182) Show SMILES Cc1cc(F)ccc1-n1c(C)nc2ccc(cc2c1=O)C(=O)c1cnn(C)c1O |(59.16,-38.71,;60.52,-39.45,;61.83,-38.65,;63.19,-39.39,;64.5,-38.59,;63.22,-40.93,;61.9,-41.73,;60.56,-40.98,;59.24,-41.78,;59.28,-43.33,;60.63,-44.08,;57.95,-44.14,;56.6,-43.39,;55.28,-44.19,;53.93,-43.44,;53.9,-41.9,;55.21,-41.11,;56.56,-41.84,;57.88,-41.03,;57.84,-39.49,;52.55,-41.16,;52.52,-39.62,;51.24,-41.95,;51.1,-43.49,;49.61,-43.84,;48.81,-42.52,;47.28,-42.4,;49.81,-41.36,;49.46,-39.86,)| Show InChI InChI=1S/C21H17FN4O3/c1-11-8-14(22)5-7-18(11)26-12(2)24-17-6-4-13(9-15(17)21(26)29)19(27)16-10-23-25(3)20(16)28/h4-10,28H,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of purified His6-tagged recombinant human HPPD assessed as inhibition of maleylacetoacetate formation after 30 mins by UV/visible spectrop...				Bioorg Med Chem 22: 5194-211 (2014) Article DOI: 10.1016/j.bmc.2014.08.011 BindingDB Entry DOI: 10.7270/Q2DF6SRG
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