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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '40S ribosomal protein S27' and Ligand = 'BDBM50420399'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
40S ribosomal protein S27


(Homo sapiens (Human))
BDBM50420399
PNG
(CHEMBL2089253)
Show SMILES CCOc1nc(Nc2ccccc2)cc(N)c1C#N
Show InChI InChI=1S/C14H14N4O/c1-2-19-14-11(9-15)12(16)8-13(18-14)17-10-6-4-3-5-7-10/h3-8H,2H2,1H3,(H3,16,17,18)
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Similars

Article
PubMed
n/an/a 228n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Mps1-mediated p38 MAPK phosphorylation after 90 mins by DELFIA assay


ACS Med Chem Lett 3: 560-564 (2012)


Article DOI: 10.1021/ml3000879
BindingDB Entry DOI: 10.7270/Q2RV0PZW
More data for this
Ligand-Target Pair