new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '5-Hydroxytryptamine receptor 6 (5-HT6)' and Ligand = 'BDBM50158042'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50158042
PNG
(1-(5-Chloro-thiophene-2-sulfonyl)-3-(1,2,3,6-tetra...)
Show SMILES Clc1ccc(s1)S(=O)(=O)n1cc(C2=CCNCC2)c2ccccc12 |t:13|
Show InChI InChI=1S/C17H15ClN2O2S2/c18-16-5-6-17(23-16)24(21,22)20-11-14(12-7-9-19-10-8-12)13-3-1-2-4-15(13)20/h1-7,11,19H,8-10H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
3n/an/an/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Binding affinity against cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells using [3H]-LSD


Bioorg Med Chem Lett 15: 379-83 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.064
BindingDB Entry DOI: 10.7270/Q20G3JNQ
More data for this
Ligand-Target Pair
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50158042
PNG
(1-(5-Chloro-thiophene-2-sulfonyl)-3-(1,2,3,6-tetra...)
Show SMILES Clc1ccc(s1)S(=O)(=O)n1cc(C2=CCNCC2)c2ccccc12 |t:13|
Show InChI InChI=1S/C17H15ClN2O2S2/c18-16-5-6-17(23-16)24(21,22)20-11-14(12-7-9-19-10-8-12)13-3-1-2-4-15(13)20/h1-7,11,19H,8-10H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 14.1n/an/an/an/an/an/a



Wyeth Research

Curated by ChEMBL


Assay Description
Inhibitory concentration against 5-HT stimulated cAMP production in HeLa cells stably transfected with human 5-HT6 receptor


Bioorg Med Chem Lett 15: 379-83 (2004)


Article DOI: 10.1016/j.bmcl.2004.10.064
BindingDB Entry DOI: 10.7270/Q20G3JNQ
More data for this
Ligand-Target Pair