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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-Hydroxytryptamine receptor 6 (5-HT6)' and Ligand = 'BDBM50228652'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50228652
PNG
(5-chloro-7-(dimethylamino)-3-methyl-3-phenylquinol...)
Show SMILES CN(C)c1cc(Cl)c2C(=O)C(C)(C(=O)Nc2c1)c1ccccc1 |w:10.10|
Show InChI InChI=1S/C18H17ClN2O2/c1-18(11-7-5-4-6-8-11)16(22)15-13(19)9-12(21(2)3)10-14(15)20-17(18)23/h4-10H,1-3H3,(H,20,23)
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Article
PubMed
715n/an/an/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]-LSD from human cloned 5HT6 receptor expressed in HEK293 cells


Bioorg Med Chem Lett 18: 738-43 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.045
BindingDB Entry DOI: 10.7270/Q2XK8F99
More data for this
Ligand-Target Pair