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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-Hydroxytryptamine receptor 6 (5-HT6)' and Ligand = 'BDBM50416111'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50416111
PNG
(CHEMBL1085361)
Show SMILES COc1ccc(c2ccccc12)S(=O)(=O)N1CC(C(=O)N2CC(N)C2)c2ccccc12
Show InChI InChI=1S/C23H23N3O4S/c1-30-21-10-11-22(18-8-3-2-7-17(18)21)31(28,29)26-14-19(16-6-4-5-9-20(16)26)23(27)25-12-15(24)13-25/h2-11,15,19H,12-14,24H2,1H3
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PC cid
PC sid
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Article
PubMed
158n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human 5HT6 expressed in CHO cells by FLIPR 384 assay


Bioorg Med Chem Lett 20: 3713-6 (2010)


Article DOI: 10.1016/j.bmcl.2010.04.085
BindingDB Entry DOI: 10.7270/Q2V69KV3
More data for this
Ligand-Target Pair