Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 1B' and Ligand = 'BDBM50054983'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50054983 (1,3-Bis-{2-[3-(2-amino-ethyl)-1H-indol-5-yloxy]-et...) Show SMILES NCCc1c[nH]c2ccc(OCCNC(=O)NCCOc3ccc4[nH]cc(CCN)c4c3)cc12 Show InChI InChI=1S/C25H32N6O3/c26-7-5-17-15-30-23-3-1-19(13-21(17)23)33-11-9-28-25(32)29-10-12-34-20-2-4-24-22(14-20)18(6-8-27)16-31-24/h1-4,13-16,30-31H,5-12,26-27H2,(H2,28,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1B receptor in CHO-K1 cells				J Med Chem 39: 4920-7 (1997) Article DOI: 10.1021/jm960552l BindingDB Entry DOI: 10.7270/Q23B5Z7M
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50054983 (1,3-Bis-{2-[3-(2-amino-ethyl)-1H-indol-5-yloxy]-et...) Show SMILES NCCc1c[nH]c2ccc(OCCNC(=O)NCCOc3ccc4[nH]cc(CCN)c4c3)cc12 Show InChI InChI=1S/C25H32N6O3/c26-7-5-17-15-30-23-3-1-19(13-21(17)23)33-11-9-28-25(32)29-10-12-34-20-2-4-24-22(14-20)18(6-8-27)16-31-24/h1-4,13-16,30-31H,5-12,26-27H2,(H2,28,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description Inhibition of forskolin-stimulated c-AMP formation by human 5-hydroxytryptamine 1B receptor expressed in CHO-K1 cells				J Med Chem 39: 4920-7 (1997) Article DOI: 10.1021/jm960552l BindingDB Entry DOI: 10.7270/Q23B5Z7M
					More data for this Ligand-Target Pair