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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2A' and Ligand = 'BDBM50018253'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50018253
PNG
(CHEMBL3290019)
Show SMILES Fc1ccc2c(noc2c1)C1CCN(CCCCNS(=O)(=O)c2cnc3ccccn23)CC1
Show InChI InChI=1S/C23H26FN5O3S/c24-18-6-7-19-20(15-18)32-27-23(19)17-8-13-28(14-9-17)11-4-2-10-26-33(30,31)22-16-25-21-5-1-3-12-29(21)22/h1,3,5-7,12,15-17,26H,2,4,8-11,13-14H2
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Similars
Article
PubMed
 9.5n/an/an/an/an/an/an/an/a



Adamed Ltd.

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from human recombinant 5-HT2A receptor expressed in CHO-K1 cell membrane after 60 mins by liquid scintillation countin...

J Med Chem 57: 4543-57 (2014)


Article DOI: 10.1021/jm401895u
BindingDB Entry DOI: 10.7270/Q2N29ZHX
More data for this
Ligand-Target Pair