BindingDB PrimarySearch

Found 6 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2A' and Ligand = 'BDBM50108306'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50108306 ((S)-1-(5,6-difluoro-1H-indol-1-yl)propan-2-amine \|...) Show SMILES C[C@H](N)Cn1ccc2cc(F)c(F)cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Tested for binding affinity of the compound towards rat 5-hydroxytryptamine 2A receptor using [3H]-Ketanserin as radioligand				Bioorg Med Chem Lett 12: 155-8 (2001) BindingDB Entry DOI: 10.7270/Q21G0KKD
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50108306 ((S)-1-(5,6-difluoro-1H-indol-1-yl)propan-2-amine \|...) Show SMILES C[C@H](N)Cn1ccc2cc(F)c(F)cc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Tested for binding affinity of the compound towards rat 5-hydroxytryptamine 2A receptor using [3H]-DOB as radioligand				Bioorg Med Chem Lett 12: 155-8 (2001) BindingDB Entry DOI: 10.7270/Q21G0KKD
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50108306 ((S)-1-(5,6-difluoro-1H-indol-1-yl)propan-2-amine \|...) Show SMILES C[C@H](N)Cn1ccc2cc(F)c(F)cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Tested for binding affinity of the compound towards human 5-hydroxytryptamine 2A receptor using [3H]-DOB as radioligand				Bioorg Med Chem Lett 12: 155-8 (2001) BindingDB Entry DOI: 10.7270/Q21G0KKD
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50108306 ((S)-1-(5,6-difluoro-1H-indol-1-yl)propan-2-amine \|...) Show SMILES C[C@H](N)Cn1ccc2cc(F)c(F)cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Inc Curated by ChEMBL					Assay Description Binding affinity against human 5-hydroxytryptamine 2A receptor using displacement of [3H]5-HT				J Med Chem 40: 2762-9 (1997) Article DOI: 10.1021/jm970030l BindingDB Entry DOI: 10.7270/Q270845Q
F. Hoffmann-La Roche Inc Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50108306 ((S)-1-(5,6-difluoro-1H-indol-1-yl)propan-2-amine \|...) Show SMILES C[C@H](N)Cn1ccc2cc(F)c(F)cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Texas Health Science Center Curated by ChEMBL					Assay Description Displacement of [3H]methylspiperone from human cloned 5HT2A receptor expressed in HEK293 cells after 90 mins by liquid scintillation counting				Bioorg Med Chem 18: 4783-92 (2011) Article DOI: 10.1016/j.bmc.2010.05.017 BindingDB Entry DOI: 10.7270/Q2V69KJ2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50108306 ((S)-1-(5,6-difluoro-1H-indol-1-yl)propan-2-amine \|...) Show SMILES C[C@H](N)Cn1ccc2cc(F)c(F)cc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Displacement of [3H]-DOB from human 5-hydroxytryptamine 2A receptor				Bioorg Med Chem Lett 12: 155-8 (2001) BindingDB Entry DOI: 10.7270/Q21G0KKD
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair