Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2A' and Ligand = 'BDBM50180252'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50180252 ((2S)-1-(6-methoxy-1H-indazol-1-yl)propan-2-amine |...) Show SMILES COc1ccc2cnn(C[C@H](C)N)c2c1 Show InChI InChI=1S/C11H15N3O/c1-8(12)7-14-11-5-10(15-2)4-3-9(11)6-13-14/h3-6,8H,7,12H2,1-2H3/t8-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]DOI from cloned human 5HT2A receptor expressed in CHO cells				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50180252 ((2S)-1-(6-methoxy-1H-indazol-1-yl)propan-2-amine |...) Show SMILES COc1ccc2cnn(C[C@H](C)N)c2c1 Show InChI InChI=1S/C11H15N3O/c1-8(12)7-14-11-5-10(15-2)4-3-9(11)6-13-14/h3-6,8H,7,12H2,1-2H3/t8-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5HT2A receptor expressed in CHO cells				Bioorg Med Chem 16: 1966-82 (2008) Article DOI: 10.1016/j.bmc.2007.10.100 BindingDB Entry DOI: 10.7270/Q2TH8NKR
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50180252 ((2S)-1-(6-methoxy-1H-indazol-1-yl)propan-2-amine |...) Show SMILES COc1ccc2cnn(C[C@H](C)N)c2c1 Show InChI InChI=1S/C11H15N3O/c1-8(12)7-14-11-5-10(15-2)4-3-9(11)6-13-14/h3-6,8H,7,12H2,1-2H3/t8-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Inhibition of [125I]DOI binding to 5HT2A receptor in rat cerebral cortex				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50180252 ((2S)-1-(6-methoxy-1H-indazol-1-yl)propan-2-amine |...) Show SMILES COc1ccc2cnn(C[C@H](C)N)c2c1 Show InChI InChI=1S/C11H15N3O/c1-8(12)7-14-11-5-10(15-2)4-3-9(11)6-13-14/h3-6,8H,7,12H2,1-2H3/t8-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	54	n/a	n/a	n/a	n/a
Alcon Research, Ltd. Curated by ChEMBL					Assay Description Activity against 5HT2A mediated intracellular calcium mobilization by FLIPR in rat vascular smooth muscle cells				J Med Chem 49: 318-28 (2006) Article DOI: 10.1021/jm050663x BindingDB Entry DOI: 10.7270/Q23B5ZQW
					More data for this Ligand-Target Pair