Found 4 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2A' and Ligand = 'BDBM50223744' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50223744
(CHEMBL155486)Show SMILES Fc1ccc2c(noc2c1)C1CCN(CC2CC(=O)c3ccccc3C2)CC1 Show InChI InChI=1S/C23H23FN2O2/c24-18-5-6-20-22(13-18)28-25-23(20)16-7-9-26(10-8-16)14-15-11-17-3-1-2-4-19(17)21(27)12-15/h1-6,13,15-16H,7-12,14H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113964 BindingDB Entry DOI: 10.7270/Q2BP06TV |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50223744
(CHEMBL155486)Show SMILES Fc1ccc2c(noc2c1)C1CCN(CC2CC(=O)c3ccccc3C2)CC1 Show InChI InChI=1S/C23H23FN2O2/c24-18-5-6-20-22(13-18)28-25-23(20)16-7-9-26(10-8-16)14-15-11-17-3-1-2-4-19(17)21(27)12-15/h1-6,13,15-16H,7-12,14H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 6.31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Santiago de Compostela
Curated by ChEMBL
| Assay Description Binding affinity towards serotonin 5-hydroxytryptamine 2A receptor |
Bioorg Med Chem Lett 14: 585-9 (2004)
BindingDB Entry DOI: 10.7270/Q2VT1V9D |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50223744
(CHEMBL155486)Show SMILES Fc1ccc2c(noc2c1)C1CCN(CC2CC(=O)c3ccccc3C2)CC1 Show InChI InChI=1S/C23H23FN2O2/c24-18-5-6-20-22(13-18)28-25-23(20)16-7-9-26(10-8-16)14-15-11-17-3-1-2-4-19(17)21(27)12-15/h1-6,13,15-16H,7-12,14H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 29.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Santiago de Compostela
Curated by ChEMBL
| Assay Description Binding affinity towards serotonin 5-hydroxytryptamine 2A receptor |
Bioorg Med Chem Lett 14: 585-9 (2004)
BindingDB Entry DOI: 10.7270/Q2VT1V9D |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50223744
(CHEMBL155486)Show SMILES Fc1ccc2c(noc2c1)C1CCN(CC2CC(=O)c3ccccc3C2)CC1 Show InChI InChI=1S/C23H23FN2O2/c24-18-5-6-20-22(13-18)28-25-23(20)16-7-9-26(10-8-16)14-15-11-17-3-1-2-4-19(17)21(27)12-15/h1-6,13,15-16H,7-12,14H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad de Santiago de Compostela
Curated by ChEMBL
| Assay Description Binding affinity towards serotonin 5-hydroxytryptamine 2A receptor |
Bioorg Med Chem Lett 14: 585-9 (2004)
BindingDB Entry DOI: 10.7270/Q2VT1V9D |
More data for this Ligand-Target Pair | |