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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2A' and Ligand = 'BDBM50302141'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50302141
PNG
(2-(2-(2-chlorophenoxy)ethyl)-6-(piperazin-1-yl)pyr...)
Show SMILES Clc1ccccc1OCCn1nc(ccc1=O)N1CCNCC1
Show InChI InChI=1S/C16H19ClN4O2/c17-13-3-1-2-4-14(13)23-12-11-21-16(22)6-5-15(19-21)20-9-7-18-8-10-20/h1-6,18H,7-12H2
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MMDB

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Similars
Article
PubMed
n/an/an/an/a 254n/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant 5HT2A receptor expressed in Swiss mouse 3T3 cells assessed as induction of calcium mobilization by FLIPR assay

Bioorg Med Chem Lett 19: 5791-5 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.136
BindingDB Entry DOI: 10.7270/Q2X0674Z
More data for this
Ligand-Target Pair