Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50324542 (2-[4-(4-Chloro-1-methyl-1H-pyrazole-3-carbonyl)pip...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals. Curated by ChEMBL | Assay Description Binding affinity to rat 5HT2A receptor | J Med Chem 53: 5696-706 (2010) Article DOI: 10.1021/jm100479q BindingDB Entry DOI: 10.7270/Q2CV4HZX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Canis familiaris) | BDBM50324542 (2-[4-(4-Chloro-1-methyl-1H-pyrazole-3-carbonyl)pip...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals. Curated by ChEMBL | Assay Description Binding affinity to dog 5HT2A receptor | J Med Chem 53: 5696-706 (2010) Article DOI: 10.1021/jm100479q BindingDB Entry DOI: 10.7270/Q2CV4HZX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50324542 (2-[4-(4-Chloro-1-methyl-1H-pyrazole-3-carbonyl)pip...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals. Curated by ChEMBL | Assay Description Displacement of [125I]DOI from human recombinant 5HT2A receptor expressed in HEK293 cells after 1 hr by scintillation counting | J Med Chem 53: 5696-706 (2010) Article DOI: 10.1021/jm100479q BindingDB Entry DOI: 10.7270/Q2CV4HZX | |||||||||||
More data for this Ligand-Target Pair |