BindingDB PrimarySearch

Found 7 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2A' and Ligand = 'BDBM85530'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM85530 (Nor-d-fenfluramine \| Nor-dexfenfluramine \| Norfenf...) Show SMILES C[C@H](N)Cc1cccc(c1)C(F)(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	151	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vernalis Research Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 370: 114-23 (2004) Article DOI: 10.1007/s00210-004-0951-4 BindingDB Entry DOI: 10.7270/Q2M32TBD
Vernalis Research Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM85530 (Nor-d-fenfluramine \| Nor-dexfenfluramine \| Norfenf...) Show SMILES C[C@H](N)Cc1cccc(c1)C(F)(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	PubMed	187	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The DuPont Pharmaceuticals Research Laboratories Curated by PDSP K_i Database									Mol Pharmacol 57: 75-81 (2000) BindingDB Entry DOI: 10.7270/Q2P26WPH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM85530 (Nor-d-fenfluramine \| Nor-dexfenfluramine \| Norfenf...) Show SMILES C[C@H](N)Cc1cccc(c1)C(F)(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cerebrus Ltd Curated by PDSP K_i Database									Br J Pharmacol 128: 13-20 (1999) Article DOI: 10.1038/sj.bjp.0702751 BindingDB Entry DOI: 10.7270/Q2GH9GH2
Cerebrus Ltd Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM85530 (Nor-d-fenfluramine \| Nor-dexfenfluramine \| Norfenf...) Show SMILES C[C@H](N)Cc1cccc(c1)C(F)(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.52E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NIH Curated by PDSP K_i Database									Circulation 102: 2836-41 (2000) Article DOI: 10.1161/01.cir.102.23.2836 BindingDB Entry DOI: 10.7270/Q2H70DD1
NIH Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM85530 (Nor-d-fenfluramine \| Nor-dexfenfluramine \| Norfenf...) Show SMILES C[C@H](N)Cc1cccc(c1)C(F)(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2.32E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NIH Curated by PDSP K_i Database									Circulation 102: 2836-41 (2000) Article DOI: 10.1161/01.cir.102.23.2836 BindingDB Entry DOI: 10.7270/Q2H70DD1
NIH Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM85530 (Nor-d-fenfluramine \| Nor-dexfenfluramine \| Norfenf...) Show SMILES C[C@H](N)Cc1cccc(c1)C(F)(F)F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	3.84E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NIH Curated by PDSP K_i Database									Circulation 102: 2836-41 (2000) Article DOI: 10.1161/01.cir.102.23.2836 BindingDB Entry DOI: 10.7270/Q2H70DD1
NIH Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM85530 (Nor-d-fenfluramine \| Nor-dexfenfluramine \| Norfenf...) Show SMILES C[C@H](N)Cc1cccc(c1)C(F)(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as intracellular IP3 accumulation				J Med Chem 51: 305-13 (2008) Article DOI: 10.1021/jm0709034 BindingDB Entry DOI: 10.7270/Q26Q211B
Arena Pharmaceuticals Inc. Curated by ChEMBL					More data for this Ligand-Target Pair