Found 5 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2B' and Ligand = 'BDBM50005257' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50005257
((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...)Show InChI InChI=1S/C11H16BrNO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3 | PDB
Reactome pathway
KEGG
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| Purchase
CHEMBL
DrugBank
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.88 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cerebrus Ltd
Curated by PDSP Ki Database
| |
Br J Pharmacol 128: 13-20 (1999)
Article DOI: 10.1038/sj.bjp.0702751
BindingDB Entry DOI: 10.7270/Q2GH9GH2 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(RAT) | BDBM50005257
((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...)Show InChI InChI=1S/C11H16BrNO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 21.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 359: 1-6 (1999)
Article DOI: 10.1007/pl00005315
BindingDB Entry DOI: 10.7270/Q2862F09 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50005257
((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...)Show InChI InChI=1S/C11H16BrNO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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antibodypedia
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| Purchase
CHEMBL
DrugBank
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 26.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 359: 1-6 (1999)
Article DOI: 10.1007/pl00005315
BindingDB Entry DOI: 10.7270/Q2862F09 |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50005257
((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...)Show InChI InChI=1S/C11H16BrNO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 43.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 370: 114-23 (2004)
Article DOI: 10.1007/s00210-004-0951-4
BindingDB Entry DOI: 10.7270/Q2M32TBD |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(RAT) | BDBM50005257
((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...)Show InChI InChI=1S/C11H16BrNO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | 44.7 | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Affinity against 5-hydroxytryptamine 2B receptor in the isolated rat stomach fundus |
J Med Chem 24: 1414-21 (1982)
BindingDB Entry DOI: 10.7270/Q2SX6FD3 |
More data for this
Ligand-Target Pair | |
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