Found 5 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2B' and Ligand = 'BDBM50007406' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50007406
(1-(3-(trifluoromethyl)phenyl)piperazine | 1-(3-Tri...)Show InChI InChI=1S/C11H13F3N2/c12-11(13,14)9-2-1-3-10(8-9)16-6-4-15-5-7-16/h1-3,8,15H,4-7H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 39.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 276: 720-7 (1996)
BindingDB Entry DOI: 10.7270/Q29W0D1S |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50007406
(1-(3-(trifluoromethyl)phenyl)piperazine | 1-(3-Tri...)Show InChI InChI=1S/C11H13F3N2/c12-11(13,14)9-2-1-3-10(8-9)16-6-4-15-5-7-16/h1-3,8,15H,4-7H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 58.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research
Curated by PDSP Ki Database
| |
Naunyn Schmiedebergs Arch Pharmacol 370: 114-23 (2004)
Article DOI: 10.1007/s00210-004-0951-4 BindingDB Entry DOI: 10.7270/Q2M32TBD |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(RAT) | BDBM50007406
(1-(3-(trifluoromethyl)phenyl)piperazine | 1-(3-Tri...)Show InChI InChI=1S/C11H13F3N2/c12-11(13,14)9-2-1-3-10(8-9)16-6-4-15-5-7-16/h1-3,8,15H,4-7H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 84.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 276: 720-7 (1996)
BindingDB Entry DOI: 10.7270/Q29W0D1S |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(RAT) | BDBM50007406
(1-(3-(trifluoromethyl)phenyl)piperazine | 1-(3-Tri...)Show InChI InChI=1S/C11H13F3N2/c12-11(13,14)9-2-1-3-10(8-9)16-6-4-15-5-7-16/h1-3,8,15H,4-7H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 85.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Alberta
Curated by PDSP Ki Database
| |
Neuropharmacology 33: 275-317 (1994)
Article DOI: 10.1016/0028-3908(94)90059-0 BindingDB Entry DOI: 10.7270/Q2M043X2 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50007406
(1-(3-(trifluoromethyl)phenyl)piperazine | 1-(3-Tri...)Show InChI InChI=1S/C11H13F3N2/c12-11(13,14)9-2-1-3-10(8-9)16-6-4-15-5-7-16/h1-3,8,15H,4-7H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 288 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cerebrus Ltd
Curated by PDSP Ki Database
| |
Br J Pharmacol 128: 13-20 (1999)
Article DOI: 10.1038/sj.bjp.0702751 BindingDB Entry DOI: 10.7270/Q2GH9GH2 |
More data for this Ligand-Target Pair | |