Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50169261 ((4R,10aS)-7-Chloro-4,6-dimethyl-1,2,3,4,10,10a-hex...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd Curated by ChEMBL | Assay Description Displacement of [3H]-5HT from human recombinant 5HT2C receptor expressed in CHO cells | Bioorg Med Chem Lett 16: 1207-11 (2006) Article DOI: 10.1016/j.bmcl.2005.11.083 BindingDB Entry DOI: 10.7270/Q21R6Q3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50169261 ((4R,10aS)-7-Chloro-4,6-dimethyl-1,2,3,4,10,10a-hex...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd. Curated by ChEMBL | Assay Description Binding affinity toward 5-HT2C receptor evaluated by displacement of [3H]-5-HT radioligand | Bioorg Med Chem Lett 15: 3604-8 (2005) Article DOI: 10.1016/j.bmcl.2005.05.074 BindingDB Entry DOI: 10.7270/Q2GQ6X87 | |||||||||||
More data for this Ligand-Target Pair |