Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50169842 (1-(2,4-difluorophenethyl)-4-fluoro-4-(4-fluorophen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 69 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp& Dohme Curated by ChEMBL | Assay Description Displacement of [3H]-mesulergine from human 5HT2C receptor expressed CHO cells | Bioorg Med Chem Lett 20: 3708-12 (2010) Article DOI: 10.1016/j.bmcl.2010.04.090 BindingDB Entry DOI: 10.7270/Q2RX9C89 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50169842 (1-(2,4-difluorophenethyl)-4-fluoro-4-(4-fluorophen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 176 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Curated by ChEMBL | Assay Description Binding affinity against human 5-hydroxytryptamine 2c receptor | Bioorg Med Chem Lett 15: 3665-9 (2005) Article DOI: 10.1016/j.bmcl.2005.05.104 BindingDB Entry DOI: 10.7270/Q2HM580P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50169842 (1-(2,4-difluorophenethyl)-4-fluoro-4-(4-fluorophen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp and Dohme Curated by ChEMBL | Assay Description Displacement of [3H]mesurgeline from human 5HT2C receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 2643-8 (2007) Article DOI: 10.1016/j.bmcl.2007.01.098 BindingDB Entry DOI: 10.7270/Q2F47PZH | |||||||||||
More data for this Ligand-Target Pair |